Revatio and Sciatica - a phase IV clinical study of FDA data

Summary:

Sciatica is reported as a side effect among people who take Revatio (sildenafil citrate), especially for people who are female, 60+ old, also take Letairis, and have Vein disorder.

The phase IV clinical study analyzes which people have Sciatica when taking Revatio. It is created by eHealthMe based on reports of 44,758 people who have side effects when taking Revatio from the FDA, and is updated regularly.

What is Revatio?

Revatio has active ingredients of sildenafil citrate. It is often used in pulmonary hypertension. eHealthMe is studying from 44,849 Revatio users. Check the latest studies of Revatio.

What is Sciatica?

Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve) is found to be associated with 1,137 drugs and 1,433 conditions by eHealthMe. Check the latest studies of Sciatica.

On Jun, 26, 2026

44,758 people reported to have side effects when taking Revatio.
Among them, 37 people (0.08%) have Sciatica.

Among these 37 people:

What is the gender of people who have Sciatica when taking Revatio? *

female: 89.19 %
male: 10.81 %

What is the age of people who have Sciatica when taking Revatio? *

What are other drugs people take besides Revatio? *

What are other side effects people have besides Sciatica? *

Pain In Extremity: 13 people, 35.14%
Dyspnea (difficult or laboured breathing): 12 people, 32.43%
Malaise (a feeling of general discomfort or uneasiness): 11 people, 29.73%
Headache (pain in head): 10 people, 27.03%
Pain: 10 people, 27.03%
Joint Pain: 9 people, 24.32%
Back Pain: 8 people, 21.62%
Nausea (feeling of having an urge to vomit): 7 people, 18.92%
Muscle Aches (muscle pain): 7 people, 18.92%
Weakness: 6 people, 16.22%

What are the existing conditions these people have? *

Vein Disorder: 3 people, 8.11%
Systemic Sclerosis (an autoimmune or connective tissue disease. it is characterized by thickening of the skin): 2 people, 5.41%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 2.70%
Hypokalemia (low potassium): 1 person, 2.70%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 1 person, 2.70%
Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 1 person, 2.70%
High Blood Pressure: 1 person, 2.70%
Gastritis - Chronic (long lasting inflammation of stomach): 1 person, 2.70%
Dyslipidaemia (abnormal amount of lipids): 1 person, 2.70%
Chronic Kidney Disease: 1 person, 2.70%

* Approximation only. Some reports may have incomplete information.

Do you take Revatio and have Sciatica?

- Check whether Sciatica is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Revatio:

Revatio (44,849 reports)

Sciatica treatments and more:

Sciatica (28,509 reports)

Browse all side effects of Revatio:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sciatica:

Sciatica (1,137 drugs)

Browse all the conditions that are associated with Sciatica:

Sciatica (1,433 conditions)

Related publications that referenced our studies

Jeong SY, Jeon SJ, Kim YR, Choi SS, Kwak HS, "A Rare Case of Viagra Induced Toxic Encephalopathy", Investigative Magnetic Resonance Imaging, 2016 Sep .
Jeong SY, Jeon SJ, Kim YR, Choi SS, Kwak HS, "A Rare Case of Viagra Induced Toxic Encephalopathy", Investigative Magnetic Resonance Imaging, 2016 Sep .

How the study uses the data?

The study uses data from the FDA. It is based on sildenafil citrate (the active ingredients of Revatio) and Revatio (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.