Revlimid and Appendix disorder - a phase IV clinical study of FDA data

Summary:

Appendix disorder is reported as a side effect among people who take Revlimid (lenalidomide), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Vitamin B12, and have Infection.

The phase IV clinical study analyzes which people have Appendix disorder when taking Revlimid. It is created by eHealthMe based on reports of 377,717 people who have side effects when taking Revlimid from the FDA, and is updated regularly.

What is Revlimid?

Revlimid has active ingredients of lenalidomide. It is often used in multiple myeloma. eHealthMe is studying from 378,026 Revlimid users. Check the latest studies of Revlimid.

What is Appendix disorder?

Appendix disorder is found to be associated with 210 drugs and 409 conditions by eHealthMe. Check the latest studies of Appendix disorder.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 01, 2026

377,717 people reported to have side effects when taking Revlimid.
Among them, 68 people (0.02%) have Appendix disorder.

Could Revlimid cause Appendix disorder?

Among these 68 people:

How long have people been on Revlimid when they have Appendix disorder? *

  • < 1 month: 20 %
  • 1 - 6 months: 20 %
  • 6 - 12 months: 20 %
  • 1 - 2 years: 20 %
  • 2 - 5 years: 20 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Appendix disorder when taking Revlimid? *

  • female: 38.24 %
  • male: 61.76 %

What is the age of people who have Appendix disorder when taking Revlimid? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 2.17 %
  • 30-39: 0.0 %
  • 40-49: 8.7 %
  • 50-59: 21.74 %
  • 60+: 67.39 %

What are other drugs people take besides Revlimid? *

  1. Vitamin D3: 5 people, 7.35%
  2. Velcade: 5 people, 7.35%
  3. Vitamin B12: 5 people, 7.35%
  4. Dexamethasone: 4 people, 5.88%
  5. Aspirin: 4 people, 5.88%
  6. Acyclovir: 4 people, 5.88%
  7. Zofran: 4 people, 5.88%
  8. Synthroid: 3 people, 4.41%
  9. Eliquis: 3 people, 4.41%
  10. Calcium: 3 people, 4.41%

What are other side effects people have besides Appendix disorder? *

  1. Diarrhea: 6 people, 8.82%
  2. Sinusitis (inflammation of sinus): 4 people, 5.88%
  3. Cough: 3 people, 4.41%
  4. Fatigue (feeling of tiredness): 3 people, 4.41%
  5. Pneumonia: 3 people, 4.41%
  6. White Blood Cell Count Decreased: 2 people, 2.94%
  7. Dyspnea (difficult or laboured breathing): 2 people, 2.94%
  8. Eye Infection: 2 people, 2.94%
  9. Fever: 2 people, 2.94%
  10. Malaise (a feeling of general discomfort or uneasiness): 2 people, 2.94%

What are the existing conditions these people have? *

  1. Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 1 person, 1.47%
  2. Seasonal Allergy (allergic condition due to certain season): 1 person, 1.47%
  3. Prostate Cancer: 1 person, 1.47%
  4. Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 1 person, 1.47%
  5. Neoplasm Malignant (cancer tumour): 1 person, 1.47%
  6. Nausea (feeling of having an urge to vomit): 1 person, 1.47%
  7. Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 1 person, 1.47%
  8. Muscle Spasms (muscle contraction): 1 person, 1.47%
  9. Mantle Cell Lymphoma (cancer of lymphocytes, a type of white blood cell): 1 person, 1.47%
  10. Infection: 1 person, 1.47%

* Approximation only. Some reports may have incomplete information.

Do you take Revlimid and have Appendix disorder?

- Check whether Appendix disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Revlimid:

Appendix disorder treatments and more:

How severe was Appendix disorder and when was it recovered:

Expand to all the drugs that have ingredients of lenalidomide:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Revlimid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Appendix disorder:

Browse all the conditions that are associated with Appendix disorder:


How the study uses the data?

The study uses data from the FDA. It is based on lenalidomide (the active ingredients of Revlimid) and Revlimid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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