Rexulti and Hot flush - a phase IV clinical study of FDA data

Summary:

Hot flush is reported as a side effect among people who take Rexulti (brexpiprazole), especially for people who are 40-49 old, have been taking the drug for < 1 month also take Buspar, and have Panic disorder.

The phase IV clinical study analyzes which people have Hot flush when taking Rexulti. It is created by eHealthMe based on reports of 13,206 people who have side effects when taking Rexulti from the FDA, and is updated regularly.

What is Rexulti?

Rexulti has active ingredients of brexpiprazole. It is often used in major depression. eHealthMe is studying from 13,394 Rexulti users. Check the latest studies of Rexulti.

What is Hot flush?

Hot flush (sudden feelings of heat) is found to be associated with 1,770 drugs and 2,343 conditions by eHealthMe. Check the latest studies of Hot flush.

On Jul, 14, 2026

13,206 people reported to have side effects when taking Rexulti.
Among them, 33 people (0.25%) have Hot flush.

Among these 33 people:

How long have people been on Rexulti when they have Hot flush? *

What is the age of people who have Hot flush when taking Rexulti? *

What are other drugs people take besides Rexulti? *

What are other side effects people have besides Hot flush? *

Tremor (trembling or shaking movements in one or more parts of your body): 12 people, 36.36%
Chills (felling of cold): 10 people, 30.30%
Suicidal Ideation: 10 people, 30.30%
Weight Increased: 7 people, 21.21%
Hyperhidrosis (abnormally increased sweating): 6 people, 18.18%
Abdominal Discomfort: 4 people, 12.12%
Diarrhea: 4 people, 12.12%
Dizziness: 4 people, 12.12%
Nausea (feeling of having an urge to vomit): 4 people, 12.12%
Oropharyngeal Pain: 3 people, 9.09%

What are the existing conditions these people have? *

Bipolar Disorder (mood disorder): 10 people, 30.30%
Panic Disorder: 10 people, 30.30%
Depression: 7 people, 21.21%
Stress And Anxiety: 3 people, 9.09%
Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 2 people, 6.06%
Insomnia (sleeplessness): 2 people, 6.06%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 2 people, 6.06%
Drowsiness: 1 person, 3.03%
Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 1 person, 3.03%
Breast Cancer Stage Ii: 1 person, 3.03%

* Approximation only. Some reports may have incomplete information.

Do you take Rexulti and have Hot flush?

- Check whether Hot flush is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Rexulti:

Rexulti (13,394 reports)

Hot flush treatments and more:

Hot flush (91,208 reports)

Browse all side effects of Rexulti:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hot flush:

Hot flush (1,770 drugs)

Browse all the conditions that are associated with Hot flush:

Hot flush (2,343 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on brexpiprazole (the active ingredients of Rexulti) and Rexulti (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.