Rezulin and Macular oedema - a phase IV clinical study of FDA data

Summary:

Macular oedema is reported as a side effect among people who take Rezulin (troglitazone), especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months also take Lasix, and have Back pain.

The phase IV clinical study analyzes which people have Macular oedema when taking Rezulin. It is created by eHealthMe based on reports of 8,761 people who have side effects when taking Rezulin from the FDA, and is updated regularly.

What is Rezulin?

Rezulin has active ingredients of troglitazone. eHealthMe is studying from 8,764 Rezulin users. Check the latest studies of Rezulin.

What is Macular oedema?

Macular oedema (fluid and protein deposits collect on or under the macula of the eye (a yellow central area of the retina) and causes it to thicken) is found to be associated with 432 drugs and 861 conditions by eHealthMe. Check the latest studies of Macular oedema.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

8,761 people reported to have side effects when taking Rezulin.
Among them, 11 people (0.13%) have Macular oedema.

Among these 11 people:

How long have people been on Rezulin when they have Macular oedema? *

What is the gender of people who have Macular oedema when taking Rezulin? *

female: 81.82 %
male: 18.18 %

What is the age of people who have Macular oedema when taking Rezulin? *

What are other drugs people take besides Rezulin? *

What are other side effects people have besides Macular oedema? *

Weight Increased: 4 people, 36.36%
Joint Pain: 4 people, 36.36%
Back Pain: 4 people, 36.36%
Nausea (feeling of having an urge to vomit): 4 people, 36.36%
High Blood Cholesterol: 3 people, 27.27%
Maculopathy (a condition or disease of the macula, the small spot in the retina where vision is keenest): 3 people, 27.27%
Weight Decreased: 3 people, 27.27%
Fatigue (feeling of tiredness): 3 people, 27.27%
Oedema Lower Limb (fluid collection in tissue of lower leg): 3 people, 27.27%
Fungal Nail Infection: 2 people, 18.18%

What are the existing conditions these people have? *

Ill-Defined Disorder: 2 people, 18.18%
High Blood Cholesterol: 2 people, 18.18%
Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 2 people, 18.18%
Diabetes: 2 people, 18.18%
Back Pain: 2 people, 18.18%

* Approximation only. Some reports may have incomplete information.

Do you take Rezulin and have Macular oedema?

- Check whether Macular oedema is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Rezulin:

Rezulin (8,764 reports)

Macular oedema treatments and more:

Macular oedema (10,661 reports)

Browse all side effects of Rezulin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Macular oedema:

Macular oedema (432 drugs)

Browse all the conditions that are associated with Macular oedema:

Macular oedema (861 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on troglitazone (the active ingredients of Rezulin) and Rezulin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.