Riboflavin and Kidney stones - a phase IV clinical study of FDA data

Summary:

Kidney stones is reported as a side effect among people who take Riboflavin (riboflavin (vitamin b2)), especially for people who are female, 40-49 old, also take Xyrem, and have Narcolepsy.

The phase IV clinical study analyzes which people have Kidney stones when taking Riboflavin. It is created by eHealthMe based on reports of 2,771 people who have side effects when taking Riboflavin from the FDA, and is updated regularly.

What is Riboflavin?

Riboflavin has active ingredients of riboflavin (vitamin b2). It is often used in migraine. eHealthMe is studying from 2,869 Riboflavin users. Check the latest studies of Riboflavin.

What is Kidney stones?

Kidney stones is found to be associated with 1,833 drugs and 2,124 conditions by eHealthMe. Check the latest studies of Kidney stones.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 25, 2026

2,771 people reported to have side effects when taking Riboflavin.
Among them, 12 people (0.43%) have Kidney stones.

Among these 12 people:

What is the gender of people who have Kidney stones when taking Riboflavin? *

female: 81.82 %
male: 18.18 %

What is the age of people who have Kidney stones when taking Riboflavin? *

What are other drugs people take besides Riboflavin? *

What are other side effects people have besides Kidney stones? *

Nausea And Vomiting: 2 people, 16.67%
Choledocholithiasis (stones in the common bile duct): 2 people, 16.67%
Uterine Disorder: 2 people, 16.67%
Malaise (a feeling of general discomfort or uneasiness): 2 people, 16.67%
Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 2 people, 16.67%
Migraine With Aura (headache with vision weakness): 2 people, 16.67%
Fall: 2 people, 16.67%
Muscle Spasms (muscle contraction): 2 people, 16.67%
Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 2 people, 16.67%
Peripheral Swelling: 2 people, 16.67%

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 9 people, 75.00%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 7 people, 58.33%
High Blood Pressure: 3 people, 25.00%
Pain: 2 people, 16.67%
Muscle Spasms (muscle contraction): 2 people, 16.67%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 16.67%
Drowsiness: 2 people, 16.67%
Ill-Defined Disorder: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Riboflavin and have Kidney stones?

- Check whether Kidney stones is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Riboflavin:

Riboflavin (2,869 reports)

Kidney stones treatments and more:

Kidney stones (59,729 reports)

Browse all side effects of Riboflavin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Kidney stones:

Kidney stones (1,833 drugs)

Browse all the conditions that are associated with Kidney stones:

Kidney stones (2,124 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on riboflavin (vitamin b2) (the active ingredients of Riboflavin) and Riboflavin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.