Rifabutin and Multi-organ failure - a phase IV clinical study of FDA data

Summary:

Multi-organ failure is reported as a side effect among people who take Rifabutin (rifabutin), especially for people who are male, 50-59 old, have been taking the drug for 1 - 6 months also take Norvir, and have Cytomegalovirus infection.

The phase IV clinical study analyzes which people have Multi-organ failure when taking Rifabutin. It is created by eHealthMe based on reports of 2,430 people who have side effects when taking Rifabutin from the FDA, and is updated regularly.

What is Rifabutin?

Rifabutin has active ingredients of rifabutin. eHealthMe is studying from 2,437 Rifabutin users. Check the latest studies of Rifabutin.

What is Multi-organ failure?

Multi-organ failure (multisystem organ failure) is found to be associated with 1,389 drugs and 2,281 conditions by eHealthMe. Check the latest studies of Multi-organ failure.

On Aug, 04, 2026

2,430 people reported to have side effects when taking Rifabutin.
Among them, 12 people (0.49%) have Multi-organ failure.

Could Rifabutin cause Multi-organ failure?

Among these 12 people:

How long have people been on Rifabutin when they have Multi-organ failure? *

What is the gender of people who have Multi-organ failure when taking Rifabutin? *

female: 50 %
male: 50 %

What is the age of people who have Multi-organ failure when taking Rifabutin? *

What are other drugs people take besides Rifabutin? *

Norvir: 8 people, 66.67%
Zithromax: 7 people, 58.33%
Ethambutol Hydrochloride: 7 people, 58.33%
Isentress: 6 people, 50.00%
Reyataz: 5 people, 41.67%
Truvada: 5 people, 41.67%
Clarithromycin: 5 people, 41.67%
Epzicom: 4 people, 33.33%
Epivir: 4 people, 33.33%
Ambisome: 4 people, 33.33%

What are other side effects people have besides Multi-organ failure? *

Histiocytosis Haematophagic: 5 people, 41.67%
Cytomegalovirus Viraemia (cytomegalo virus in blood stream): 4 people, 33.33%
Pleural Effusion (water on the lungs): 4 people, 33.33%
Aids Encephalopathy (malfunction of the brain as a result of hiv infection, variety of cognitive, motor, and behavioural abnormalities): 4 people, 33.33%
Pancreatitis (inflammation of pancreas): 4 people, 33.33%
Disseminated Intravascular Coagulation (systemic activation of blood coagulation): 4 people, 33.33%
Atypical Mycobacterial Infection (infections caused by several types of mycobacterium similar to the germ that causes tuberculosis): 4 people, 33.33%
International Normalised Ratio Increased: 3 people, 25.00%
Markedly Reduced Food Intake: 3 people, 25.00%
Liver Function Tests Nos Abnormal: 3 people, 25.00%

What are the existing conditions these people have? *

Cytomegalovirus Infection: 5 people, 41.67%
Mycobacterium Avium Complex Infection: 4 people, 33.33%
Kaposi's Sarcoma Aids Related (a tumour caused by human herpes virus associated with aids): 4 people, 33.33%
Hiv Infection: 4 people, 33.33%
White Blood Cell Count Decreased: 3 people, 25.00%
Joint Pain: 1 person, 8.33%
Cerebral Toxoplasmosis (parasitic disease of brain caused by the protozoan toxoplasma gondii): 1 person, 8.33%
Birth Control: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Rifabutin and have Multi-organ failure?

- Check whether Multi-organ failure is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Rifabutin:

Rifabutin (2,437 reports)

Browse all side effects of Rifabutin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Multi-organ failure:

Multi-organ failure (1,389 drugs)

Browse all the conditions that are associated with Multi-organ failure:

Multi-organ failure (2,281 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on rifabutin (the active ingredients of Rifabutin) and Rifabutin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.