Rinvoq and Defaecation urgency - a phase IV clinical study of FDA data

Summary:

Defaecation urgency is reported as a side effect among people who take Rinvoq (upadacitinib), especially for people who are female, 30-39 old, have been taking the drug for 1 - 6 months also take Skyrizi, and have Ulcerative colitis.

The phase IV clinical study analyzes which people have Defaecation urgency when taking Rinvoq. It is created by eHealthMe based on reports of 47,330 people who have side effects when taking Rinvoq from the FDA, and is updated regularly.

What is Rinvoq?

Rinvoq has active ingredients of upadacitinib. eHealthMe is studying from 47,375 Rinvoq users. Check the latest studies of Rinvoq.

What is Defaecation urgency?

Defaecation urgency (a sudden compelling urge to defecate) is found to be associated with 538 drugs and 518 conditions by eHealthMe. Check the latest studies of Defaecation urgency.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

47,330 people reported to have side effects when taking Rinvoq.
Among them, 35 people (0.07%) have Defaecation urgency.

Among these 35 people:

How long have people been on Rinvoq when they have Defaecation urgency? *

What is the gender of people who have Defaecation urgency when taking Rinvoq? *

female: 52.94 %
male: 47.06 %

What is the age of people who have Defaecation urgency when taking Rinvoq? *

What are other drugs people take besides Rinvoq? *

What are other side effects people have besides Defaecation urgency? *

Fatigue (feeling of tiredness): 12 people, 34.29%
Abdominal Pain: 11 people, 31.43%
Diarrhea: 11 people, 31.43%
Joint Pain: 9 people, 25.71%
Flatulence (flatus expelled through the anus): 9 people, 25.71%
Constipation: 7 people, 20.00%
Weakness: 6 people, 17.14%
Drug Ineffective: 6 people, 17.14%
Insomnia (sleeplessness): 6 people, 17.14%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 5 people, 14.29%

What are the existing conditions these people have? *

Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 19 people, 54.29%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 6 people, 17.14%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 14.29%
Hypersensitivity: 1 person, 2.86%
Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 1 person, 2.86%

* Approximation only. Some reports may have incomplete information.

Do you take Rinvoq and have Defaecation urgency?

- Check whether Defaecation urgency is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Rinvoq:

Rinvoq (47,375 reports)

Browse all side effects of Rinvoq:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Defaecation urgency:

Defaecation urgency (538 drugs)

Browse all the conditions that are associated with Defaecation urgency:

Defaecation urgency (518 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on upadacitinib (the active ingredients of Rinvoq) and Rinvoq (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.