Rinvoq and Papule - a phase IV clinical study of FDA data

Summary:

Papule is reported as a side effect among people who take Rinvoq (upadacitinib), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Omeprazole, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Papule when taking Rinvoq. It is created by eHealthMe based on reports of 47,330 people who have side effects when taking Rinvoq from the FDA, and is updated regularly.

What is Rinvoq?

Rinvoq has active ingredients of upadacitinib. eHealthMe is studying from 47,375 Rinvoq users. Check the latest studies of Rinvoq.

What is Papule?

Papule is found to be associated with 584 drugs and 657 conditions by eHealthMe. Check the latest studies of Papule.



On Jul, 15, 2026

47,330 people reported to have side effects when taking Rinvoq.
Among them, 48 people (0.1%) have Papule.

Could Rinvoq cause Papule?

Among these 48 people:

How long have people been on Rinvoq when they have Papule? *

  • < 1 month: 20 %
  • 1 - 6 months: 60 %
  • 6 - 12 months: 20 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Papule when taking Rinvoq? *

  • female: 72.73 %
  • male: 27.27 %

What is the age of people who have Papule when taking Rinvoq? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 5.56 %
  • 20-29: 5.56 %
  • 30-39: 5.56 %
  • 40-49: 5.56 %
  • 50-59: 0.0 %
  • 60+: 77.78 %

What are other drugs people take besides Rinvoq? *

  1. Prednisolone: 4 people, 8.33%
  2. Omeprazole: 4 people, 8.33%
  3. Arava: 3 people, 6.25%
  4. Claritin: 3 people, 6.25%
  5. Cymbalta: 2 people, 4.17%
  6. Famotidine: 2 people, 4.17%
  7. Vitamin D3: 2 people, 4.17%
  8. Ozempic: 2 people, 4.17%
  9. Xeljanz Xr: 2 people, 4.17%
  10. Vitamin D: 2 people, 4.17%

What are other side effects people have besides Papule? *

  1. Joint Pain: 12 people, 25.00%
  2. Pain: 9 people, 18.75%
  3. Head Injury: 7 people, 14.58%
  4. Rashes (redness): 6 people, 12.50%
  5. Back Pain: 6 people, 12.50%
  6. Pain In Extremity: 6 people, 12.50%
  7. Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 6 people, 12.50%
  8. Itching: 5 people, 10.42%
  9. Arthropathy: 5 people, 10.42%
  10. Skin Burning Sensation: 5 people, 10.42%

What are the existing conditions these people have? *

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 31 people, 64.58%
  2. High Blood Pressure: 5 people, 10.42%
  3. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 8.33%
  4. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 8.33%
  5. Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 3 people, 6.25%
  6. High Blood Cholesterol: 3 people, 6.25%
  7. Seasonal Allergy (allergic condition due to certain season): 3 people, 6.25%
  8. Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 3 people, 6.25%
  9. Skin Infection: 2 people, 4.17%
  10. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 2 people, 4.17%

* Approximation only. Some reports may have incomplete information.

Do you take Rinvoq and have Papule?

- Check whether Papule is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Rinvoq:

Papule treatments and more:

How severe was Papule and when was it recovered:

Expand to all the drugs that have ingredients of upadacitinib:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Rinvoq:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Papule:

Browse all the conditions that are associated with Papule:


How the study uses the data?

The study uses data from the FDA. It is based on upadacitinib (the active ingredients of Rinvoq) and Rinvoq (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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