Risperdal and Left ventricular hypertrophy - a phase IV clinical study of FDA data

Summary:

Left ventricular hypertrophy is reported as a side effect among people who take Risperdal (risperidone), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Digoxin, and have Schizophrenia, paranoid type.

The phase IV clinical study analyzes which people have Left ventricular hypertrophy when taking Risperdal. It is created by eHealthMe based on reports of 126,253 people who have side effects when taking Risperdal from the FDA, and is updated regularly.

What is Risperdal?

Risperdal has active ingredients of risperidone. It is often used in bipolar disorder. eHealthMe is studying from 127,729 Risperdal users. Check the latest studies of Risperdal.

What is Left ventricular hypertrophy?

Left ventricular hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart) is found to be associated with 899 drugs and 755 conditions by eHealthMe. Check the latest studies of Left ventricular hypertrophy.

On Jul, 11, 2026

126,253 people reported to have side effects when taking Risperdal.
Among them, 53 people (0.04%) have Left ventricular hypertrophy.

Could Risperdal cause Left ventricular hypertrophy?

Among these 53 people:

How long have people been on Risperdal when they have Left ventricular hypertrophy? *

What is the gender of people who have Left ventricular hypertrophy when taking Risperdal? *

female: 30.77 %
male: 69.23 %

What is the age of people who have Left ventricular hypertrophy when taking Risperdal? *

What are other drugs people take besides Risperdal? *

What are other side effects people have besides Left ventricular hypertrophy? *

Arrhythmias (irregular heartbeat): 16 people, 30.19%
Cardiac Failure Congestive: 14 people, 26.42%
Enlarged Heart: 12 people, 22.64%
Chest Pain: 12 people, 22.64%
Pulmonary Oedema (fluid accumulation in the lungs): 12 people, 22.64%
Oedema Peripheral (superficial swelling): 11 people, 20.75%
High Blood Pressure: 11 people, 20.75%
Stress And Anxiety: 11 people, 20.75%
Confusional State: 11 people, 20.75%
Pleural Effusion (water on the lungs): 11 people, 20.75%

What are the existing conditions these people have? *

Schizophrenia, Paranoid Type (delusions and auditory hallucinations but relatively normal intellectual functioning and expression of affect): 11 people, 20.75%
Depression: 6 people, 11.32%
Stress And Anxiety: 5 people, 9.43%
Schizoaffective Disorder (a mental disorder characterized by disordered thought): 4 people, 7.55%
Oesophageal Carcinoma (cancer tumour of oesophagus): 3 people, 5.66%
Myoclonic Epilepsy (type of epilepsy with quick little jerks of the arms, shoulder, or occasionally the legs): 2 people, 3.77%
Heart Rate Irregular: 2 people, 3.77%
High Blood Pressure: 2 people, 3.77%
Sleep Disorder: 2 people, 3.77%
Ill-Defined Disorder: 2 people, 3.77%

* Approximation only. Some reports may have incomplete information.

Do you take Risperdal and have Left ventricular hypertrophy?

- Check whether Left ventricular hypertrophy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Risperdal:

Risperdal (127,729 reports)

Browse all side effects of Risperdal:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Left ventricular hypertrophy:

Left ventricular hypertrophy (899 drugs)

Browse all the conditions that are associated with Left ventricular hypertrophy:

Left ventricular hypertrophy (755 conditions)

Related publications that referenced our studies

Janardhana P, Nagaraj AK, Basavanna PL, "Risperidone-induced skin rash", Indian journal of psychiatry, 2016 Jan .
Dsouza MC, "Could risperidone have caused the cataract?: A case report and review of literature", Journal of Research in Psychiatry and Behavioral Science, 2015 Jan .
Dsouza MC, "COULD RISPERIDONE HAVE CAUSED THE CATARACT", JRPBS, 2015 Jan .
Ray RK, Bashir MA, Rao S, "Co-Administration of Risperidone and Sodium Valproate Causing Bilateral Chronic Exertional Lower Leg Compartment Syndrome", Open Journal of Orthopedics, 2014 Apr .
Hosseini, S. H., & Ahmadi, A., "Peripheral edema occurring during treatment with risperidone combined with citalopram", Case reports in medicine, 2012 Jan .
Janardhana P, Nagaraj AK, Basavanna PL, "Risperidone-induced skin rash", Indian journal of psychiatry, 2016 Jan .
Dsouza MC, "Could risperidone have caused the cataract?: A case report and review of literature", Journal of Research in Psychiatry and Behavioral Science, 2015 Jan .
Dsouza MC, "COULD RISPERIDONE HAVE CAUSED THE CATARACT", JRPBS, 2015 Jan .
Ray RK, Bashir MA, Rao S, "Co-Administration of Risperidone and Sodium Valproate Causing Bilateral Chronic Exertional Lower Leg Compartment Syndrome", Open Journal of Orthopedics, 2014 Apr .
Hosseini, S. H., & Ahmadi, A., "Peripheral edema occurring during treatment with risperidone combined with citalopram", Case reports in medicine, 2012 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on risperidone (the active ingredients of Risperdal) and Risperdal (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.