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Ritalin la and Therapeutic response decreased - a phase IV clinical study of FDA data

Summary:

Therapeutic response decreased is reported as a side effect among people who take Ritalin la (methylphenidate hydrochloride), especially for people who are male, 2-9 old, have been taking the drug for < 1 month also take Xyrem, and have Sleep disorder.

The phase IV clinical study analyzes which people have Therapeutic response decreased when taking Ritalin la. It is created by eHealthMe based on reports of 2,254 people who have side effects when taking Ritalin la from the FDA, and is updated regularly.

What is Ritalin la?

Ritalin la has active ingredients of methylphenidate hydrochloride. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 2,563 Ritalin la users. Check the latest studies of Ritalin la.

What is Therapeutic response decreased?

Therapeutic response decreased (less preventive response) is found to be associated with 1,458 drugs and 1,579 conditions by eHealthMe. Check the latest studies of Therapeutic response decreased.

On Jul, 14, 2026

2,254 people reported to have side effects when taking Ritalin la.
Among them, 13 people (0.58%) have Therapeutic response decreased.

Could Ritalin la cause Therapeutic response decreased?

Among these 13 people:

How long have people been on Ritalin la when they have Therapeutic response decreased? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Therapeutic response decreased when taking Ritalin la? *

  • female: 30.77 %
  • male: 69.23 %

What is the age of people who have Therapeutic response decreased when taking Ritalin la? *

  • 0-1: 0.0 %
  • 2-9: 66.67 %
  • 10-19: 16.67 %
  • 20-29: 16.67 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 0.0 %

What are other drugs people take besides Ritalin la? *

  1. Xyrem: 6 people, 46.15%
  2. Ritalin: 5 people, 38.46%
  3. Prozac: 2 people, 15.38%
  4. Zoloft: 1 person, 7.69%
  5. Imitrex: 1 person, 7.69%
  6. Multivitamin: 1 person, 7.69%
  7. Miralax: 1 person, 7.69%
  8. Maxalt-Mlt: 1 person, 7.69%
  9. Lysine: 1 person, 7.69%
  10. Lyrica: 1 person, 7.69%

What are other side effects people have besides Therapeutic response decreased? *

  1. Stress And Anxiety: 4 people, 30.77%
  2. Disturbance In Attention: 2 people, 15.38%
  3. Sleep Disorder: 2 people, 15.38%
  4. Asthma: 2 people, 15.38%
  5. Nausea And Vomiting: 2 people, 15.38%
  6. Drug Ineffective: 1 person, 7.69%
  7. Generalized Anxiety Disorder (excessive, uncontrollable, unexplained and often irrational worry): 1 person, 7.69%
  8. General Symptom: 1 person, 7.69%
  9. Foot Fracture: 1 person, 7.69%
  10. Feeling Cold: 1 person, 7.69%

What are the existing conditions these people have? *

  1. Stress And Anxiety: 2 people, 15.38%
  2. Sleep Disorder: 2 people, 15.38%
  3. Small For Dates Baby (an unborn baby is growing more slowly and is smaller than most babies are at the same age): 1 person, 7.69%
  4. Psychomotor Hyperactivity (feelings of extreme restlessness): 1 person, 7.69%
  5. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 7.69%
  6. Foetal Growth Restriction (poor growth of a baby while in the mother's womb during pregnancy): 1 person, 7.69%
  7. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 1 person, 7.69%
  8. Body Height Below Normal: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Ritalin la and have Therapeutic response decreased?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ritalin la:

Therapeutic response decreased treatments and more:

How severe was Therapeutic response decreased and when was it recovered:

Expand to all the drugs that have ingredients of methylphenidate hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ritalin la:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Therapeutic response decreased:

Browse all the conditions that are associated with Therapeutic response decreased:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on methylphenidate hydrochloride (the active ingredients of Ritalin la) and Ritalin la (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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