Ritonavir and Cardiotoxicity - a phase IV clinical study of FDA data

Summary:

Cardiotoxicity is reported as a side effect among people who take Ritonavir (ritonavir), especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months also take Pantoprazole, and have Hiv infection.

The phase IV clinical study analyzes which people have Cardiotoxicity when taking Ritonavir. It is created by eHealthMe based on reports of 13,026 people who have side effects when taking Ritonavir from the FDA, and is updated regularly.

What is Ritonavir?

Ritonavir has active ingredients of ritonavir. eHealthMe is studying from 13,036 Ritonavir users. Check the latest studies of Ritonavir.

What is Cardiotoxicity?

Cardiotoxicity (damage to the heart muscle) is found to be associated with 384 drugs and 511 conditions by eHealthMe. Check the latest studies of Cardiotoxicity.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 30, 2026

13,026 people reported to have side effects when taking Ritonavir.
Among them, 13 people (0.1%) have Cardiotoxicity.

Could Ritonavir cause Cardiotoxicity?

Among these 13 people:

How long have people been on Ritonavir when they have Cardiotoxicity? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 100 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Cardiotoxicity when taking Ritonavir? *

  • female: 58.33 %
  • male: 41.67 %

What is the age of people who have Cardiotoxicity when taking Ritonavir? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 45.45 %
  • 60+: 54.55 %

What are other drugs people take besides Ritonavir? *

  1. Pantoprazole: 7 people, 53.85%
  2. Prezista: 3 people, 23.08%
  3. Darunavir: 3 people, 23.08%
  4. Acetylsalicylic Acid: 3 people, 23.08%
  5. Vancomycin: 2 people, 15.38%
  6. Heparin: 2 people, 15.38%

What are other side effects people have besides Cardiotoxicity? *

  1. Fainting (loss of consciousness and postural tone): 3 people, 23.08%
  2. Arrhythmias (irregular heartbeat): 3 people, 23.08%
  3. Bradycardia (abnormally slow heart action): 3 people, 23.08%
  4. Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system): 2 people, 15.38%
  5. Sinus Tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node): 1 person, 7.69%
  6. Bundle Branch Block Left (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the left ventricle): 1 person, 7.69%
  7. Circulatory Collapse: 1 person, 7.69%
  8. Confusional State: 1 person, 7.69%
  9. Disseminated Intravascular Coagulation (systemic activation of blood coagulation): 1 person, 7.69%
  10. Hepatic Failure (liver failure): 1 person, 7.69%

What are the existing conditions these people have? *

  1. Hiv Infection: 9 people, 69.23%
  2. Dyslipidaemia (abnormal amount of lipids): 7 people, 53.85%
  3. Cardiac Disorder: 4 people, 30.77%
  4. Hepatitis C Virus Test Positive: 3 people, 23.08%
  5. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 23.08%
  6. Pain: 2 people, 15.38%
  7. Pneumonia: 1 person, 7.69%
  8. Acquired Immunodeficiency Syndrome (disease of the human immune system caused by the human immunodeficiency virus (hiv)): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Ritonavir and have Cardiotoxicity?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ritonavir:

Cardiotoxicity treatments and more:

How severe was Cardiotoxicity and when was it recovered:

Expand to all the drugs that have ingredients of ritonavir:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ritonavir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Cardiotoxicity:

Browse all the conditions that are associated with Cardiotoxicity:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on ritonavir (the active ingredients of Ritonavir) and Ritonavir (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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