Rituxan and Fluid overload - a phase IV clinical study of FDA data

Summary:

Fluid overload is reported as a side effect among people who take Rituxan (rituximab), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Soliris, and have Chronic lymphocytic leukaemia.

The phase IV clinical study analyzes which people have Fluid overload when taking Rituxan. It is created by eHealthMe based on reports of 64,282 people who have side effects when taking Rituxan from the FDA, and is updated regularly.

What is Rituxan?

Rituxan has active ingredients of rituximab. It is often used in rheumatoid arthritis. eHealthMe is studying from 64,791 Rituxan users. Check the latest studies of Rituxan.

What is Fluid overload?

Fluid overload (too much fluid in the blood) is found to be associated with 1,031 drugs and 1,050 conditions by eHealthMe. Check the latest studies of Fluid overload.

On Jul, 06, 2026

64,282 people reported to have side effects when taking Rituxan.
Among them, 45 people (0.07%) have Fluid overload.

Among these 45 people:

How long have people been on Rituxan when they have Fluid overload? *

What is the gender of people who have Fluid overload when taking Rituxan? *

female: 57.14 %
male: 42.86 %

What is the age of people who have Fluid overload when taking Rituxan? *

What are other drugs people take besides Rituxan? *

What are other side effects people have besides Fluid overload? *

Dyspnea (difficult or laboured breathing): 14 people, 31.11%
High Blood Pressure: 12 people, 26.67%
Fatigue (feeling of tiredness): 11 people, 24.44%
Nausea (feeling of having an urge to vomit): 11 people, 24.44%
Thrombocytopenia (decrease of platelets in blood): 10 people, 22.22%
Cardiac Failure Congestive: 7 people, 15.56%
Hypotension (abnormally low blood pressure): 7 people, 15.56%
Cough: 7 people, 15.56%
Pleural Effusion (water on the lungs): 7 people, 15.56%
Weakness: 6 people, 13.33%

What are the existing conditions these people have? *

Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 8 people, 17.78%
Lymphoma (cancer that begins in immune system cells): 6 people, 13.33%
Haemolytic Uraemic Syndrome (blood clotting disease caused by e. coli infection, birth control pills, pneumonia, medications, and more): 5 people, 11.11%
Thrombocytopenia (decrease of platelets in blood): 4 people, 8.89%
Antiphospholipid Syndrome (disorder that manifests clinically as recurrent venous or arterial thrombosis and/or fetal loss): 3 people, 6.67%
Raynaud's Phenomenon (discoloration of the fingers, toes, and occasionally other areas): 2 people, 4.44%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 2 people, 4.44%
Pain: 2 people, 4.44%
Cardiac Failure Chronic: 2 people, 4.44%
High Blood Cholesterol: 2 people, 4.44%

* Approximation only. Some reports may have incomplete information.

Do you take Rituxan and have Fluid overload?

- Check whether Fluid overload is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Rituxan:

Rituxan (64,791 reports)

Fluid overload treatments and more:

Fluid overload (20,385 reports)

Browse all side effects of Rituxan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Fluid overload:

Fluid overload (1,031 drugs)

Browse all the conditions that are associated with Fluid overload:

Fluid overload (1,050 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on rituximab (the active ingredients of Rituxan) and Rituxan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.