Rituxan and Grand mal convulsion - a phase IV clinical study of FDA data

Summary:

Grand mal convulsion is reported as a side effect among people who take Rituxan (rituximab), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Cyclophosphamide, and have Chronic lymphocytic leukaemia.

The phase IV clinical study analyzes which people have Grand mal convulsion when taking Rituxan. It is created by eHealthMe based on reports of 64,282 people who have side effects when taking Rituxan from the FDA, and is updated regularly.

What is Rituxan?

Rituxan has active ingredients of rituximab. It is often used in rheumatoid arthritis. eHealthMe is studying from 64,791 Rituxan users. Check the latest studies of Rituxan.

What is Grand mal convulsion?

Grand mal convulsion (a type of generalized seizure that affects the entire brain) is found to be associated with 921 drugs and 1,337 conditions by eHealthMe. Check the latest studies of Grand mal convulsion.



On Jul, 21, 2026

64,282 people reported to have side effects when taking Rituxan.
Among them, 18 people (0.03%) have Grand mal convulsion.

Could Rituxan cause Grand mal convulsion?

Among these 18 people:

How long have people been on Rituxan when they have Grand mal convulsion? *

  • < 1 month: 50 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 50 %
  • 10+ years: 0.0 %

What is the gender of people who have Grand mal convulsion when taking Rituxan? *

  • female: 68.75 %
  • male: 31.25 %

What is the age of people who have Grand mal convulsion when taking Rituxan? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 23.08 %
  • 30-39: 0.0 %
  • 40-49: 7.69 %
  • 50-59: 7.69 %
  • 60+: 61.54 %

What are other drugs people take besides Rituxan? *

  1. Prednisone: 5 people, 27.78%
  2. Cyclophosphamide: 5 people, 27.78%
  3. Methylprednisolone: 3 people, 16.67%
  4. Digoxin: 2 people, 11.11%
  5. Lasix: 2 people, 11.11%
  6. Vincristine Sulfate: 1 person, 5.56%
  7. Atenolol: 1 person, 5.56%
  8. Avastin: 1 person, 5.56%
  9. Capecitabine: 1 person, 5.56%
  10. Cefuroxime: 1 person, 5.56%

What are other side effects people have besides Grand mal convulsion? *

  1. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 2 people, 11.11%
  2. Tumor Lysis Syndrome: 2 people, 11.11%
  3. Thrombocytopenia (decrease of platelets in blood): 2 people, 11.11%
  4. Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 2 people, 11.11%
  5. Loss Of Consciousness: 2 people, 11.11%
  6. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 2 people, 11.11%
  7. Pleural Effusion (water on the lungs): 2 people, 11.11%
  8. Fever: 2 people, 11.11%
  9. High Blood Pressure: 2 people, 11.11%
  10. Dyspnea (difficult or laboured breathing): 1 person, 5.56%

What are the existing conditions these people have? *

  1. Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 2 people, 11.11%
  2. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 2 people, 11.11%
  3. Waldenstrom's Macroglobulinaemia (cancer affects small lymphocytes (white blood cells)): 1 person, 5.56%
  4. Cryoglobulinaemia (blood contains large amounts of cryoglobulins - proteins): 1 person, 5.56%
  5. Burkitt's Lymphoma (cancer of the lymphatic system): 1 person, 5.56%
  6. Adenocarcinoma Pancreas (cancer of pancreas): 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Rituxan and have Grand mal convulsion?

- Check whether Grand mal convulsion is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Rituxan:

Grand mal convulsion treatments and more:

How severe was Grand mal convulsion and when was it recovered:

Expand to all the drugs that have ingredients of rituximab:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Rituxan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Grand mal convulsion:

Browse all the conditions that are associated with Grand mal convulsion:


How the study uses the data?

The study uses data from the FDA. It is based on rituximab (the active ingredients of Rituxan) and Rituxan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: