Rituxan and Hypothermia - a phase IV clinical study of FDA data

Summary:

Hypothermia is reported as a side effect among people who take Rituxan (rituximab), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Prednisone, and have Immunodeficiency.

The phase IV clinical study analyzes which people have Hypothermia when taking Rituxan. It is created by eHealthMe based on reports of 64,282 people who have side effects when taking Rituxan from the FDA, and is updated regularly.

What is Rituxan?

Rituxan has active ingredients of rituximab. It is often used in rheumatoid arthritis. eHealthMe is studying from 64,791 Rituxan users. Check the latest studies of Rituxan.

What is Hypothermia?

Hypothermia (body temperature drops below the required temperature for normal metabolism and body functions) is found to be associated with 782 drugs and 993 conditions by eHealthMe. Check the latest studies of Hypothermia.



On Jul, 17, 2026

64,282 people reported to have side effects when taking Rituxan.
Among them, 17 people (0.03%) have Hypothermia.

Could Rituxan cause Hypothermia?

Among these 17 people:

How long have people been on Rituxan when they have Hypothermia? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 100 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Hypothermia when taking Rituxan? *

  • female: 68.75 %
  • male: 31.25 %

What is the age of people who have Hypothermia when taking Rituxan? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 20 %
  • 40-49: 20 %
  • 50-59: 20 %
  • 60+: 40 %

What are other drugs people take besides Rituxan? *

  1. Prednisone: 6 people, 35.29%
  2. Methotrexate: 5 people, 29.41%
  3. Lexapro: 5 people, 29.41%
  4. Zyrtec: 4 people, 23.53%
  5. Miralax: 4 people, 23.53%
  6. Lisinopril: 4 people, 23.53%
  7. Levothyroxine Sodium: 4 people, 23.53%
  8. Kale: 4 people, 23.53%
  9. Imuran: 4 people, 23.53%
  10. Furosemide: 4 people, 23.53%

What are other side effects people have besides Hypothermia? *

  1. Fever: 10 people, 58.82%
  2. Chills (felling of cold): 8 people, 47.06%
  3. Abdominal Distension: 7 people, 41.18%
  4. Dizziness: 5 people, 29.41%
  5. Cough: 5 people, 29.41%
  6. Fatigue (feeling of tiredness): 5 people, 29.41%
  7. Carpal Tunnel Syndrome (nerve compression at wrist results numbness weakness, pain , swelling): 4 people, 23.53%
  8. Chest Pain: 4 people, 23.53%
  9. Nausea (feeling of having an urge to vomit): 4 people, 23.53%
  10. Multiple Allergies (allergy to multiple agents): 4 people, 23.53%

What are the existing conditions these people have? *

  1. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 4 people, 23.53%
  2. Immunodeficiency: 4 people, 23.53%
  3. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 17.65%
  4. Gastrointestinal Hypomotility (less activity of the intestinal tract): 3 people, 17.65%
  5. Encephalomyelitis (inflammation of the brain and spinal cord): 3 people, 17.65%
  6. Encephalitis (inflammation of the brain): 3 people, 17.65%
  7. Bruxism (habitual grinding of the teeth, typically during sleep): 3 people, 17.65%
  8. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 2 people, 11.76%
  9. Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 1 person, 5.88%
  10. Immunodeficiency Common Variable: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Rituxan and have Hypothermia?

- Check whether Hypothermia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Rituxan:

Hypothermia treatments and more:

How severe was Hypothermia and when was it recovered:

Expand to all the drugs that have ingredients of rituximab:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Rituxan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypothermia:

Browse all the conditions that are associated with Hypothermia:


How the study uses the data?

The study uses data from the FDA. It is based on rituximab (the active ingredients of Rituxan) and Rituxan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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