Rituxan and Menopause - a phase IV clinical study of FDA data

Summary:

Menopause is reported as a side effect among people who take Rituxan (rituximab), especially for people who are 40-49 old, have been taking the drug for < 1 month also take Methotrexate, and have Dermatomyositis.

The phase IV clinical study analyzes which people have Menopause when taking Rituxan. It is created by eHealthMe based on reports of 64,282 people who have side effects when taking Rituxan from the FDA, and is updated regularly.

What is Rituxan?

Rituxan has active ingredients of rituximab. It is often used in rheumatoid arthritis. eHealthMe is studying from 64,791 Rituxan users. Check the latest studies of Rituxan.

What is Menopause?

Menopause (end of monthly cycles in women) is found to be associated with 400 drugs and 488 conditions by eHealthMe. Check the latest studies of Menopause.



On Aug, 10, 2026

64,282 people reported to have side effects when taking Rituxan.
Among them, 27 people (0.04%) have Menopause.

Could Rituxan cause Menopause?

Among these 27 people:

How long have people been on Rituxan when they have Menopause? *

  • < 1 month: 25 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 25 %
  • 1 - 2 years: 25 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 25 %

What is the age of people who have Menopause when taking Rituxan? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 60.87 %
  • 50-59: 39.13 %
  • 60+: 0.0 %

What are other drugs people take besides Rituxan? *

  1. Methotrexate: 11 people, 40.74%
  2. Arthrotec: 10 people, 37.04%
  3. Effexor: 10 people, 37.04%
  4. Restasis: 8 people, 29.63%
  5. Tylenol: 8 people, 29.63%
  6. Synthroid: 8 people, 29.63%
  7. Diphenhydramine Hydrochloride: 7 people, 25.93%
  8. Folic Acid: 7 people, 25.93%
  9. Methylprednisolone: 7 people, 25.93%
  10. Acetaminophen: 7 people, 25.93%

What are other side effects people have besides Menopause? *

  1. Infusion Related Reaction: 14 people, 51.85%
  2. Pain: 14 people, 51.85%
  3. Fatigue (feeling of tiredness): 13 people, 48.15%
  4. Joint Pain: 12 people, 44.44%
  5. Drug Hypersensitivity: 11 people, 40.74%
  6. Blood Pressure Fluctuation: 10 people, 37.04%
  7. Eye Disorder: 10 people, 37.04%
  8. Oxygen Saturation Decreased: 10 people, 37.04%
  9. Abdominal Discomfort: 10 people, 37.04%
  10. Thermal Burn (burn by heat): 10 people, 37.04%

What are the existing conditions these people have? *

  1. Polymyositis (inflammatory muscle disease that causes weakness of the skeletal muscles): 4 people, 14.81%
  2. Dermatomyositis (inflammation of the skin and underlying muscle tissue, typically occurring as an autoimmune condition or associated with internal cancer): 4 people, 14.81%
  3. Contrast Media Allergy (reaction associated with the use of intravenous contrast material during radiology): 2 people, 7.41%
  4. Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 1 person, 3.70%
  5. Pain: 1 person, 3.70%
  6. Myelitis Transverse (a neurological condition consisting of an inflammatory process of the spinal cord): 1 person, 3.70%
  7. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 3.70%
  8. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 1 person, 3.70%

* Approximation only. Some reports may have incomplete information.

Do you take Rituxan and have Menopause?

- Check whether Menopause is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Rituxan:

Menopause treatments and more:

How severe was Menopause and when was it recovered:

Expand to all the drugs that have ingredients of rituximab:

Sub-studies by age:

0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Rituxan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Menopause:

Browse all the conditions that are associated with Menopause:


How the study uses the data?

The study uses data from the FDA. It is based on rituximab (the active ingredients of Rituxan) and Rituxan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: