Rituxan and Retinal detachment - a phase IV clinical study of FDA data
Summary:
Retinal detachment is reported as a side effect among people who take Rituxan (rituximab), especially for people who are female, 60+ old, have been taking the drug for 1 - 2 years also take Singulair, and have Chronic graft versus host disease.
The phase IV clinical study analyzes which people have Retinal detachment when taking Rituxan. It is created by eHealthMe based on reports of 64,282 people who have side effects when taking Rituxan from the FDA, and is updated regularly.
What is Rituxan?
Rituxan has active ingredients of rituximab. It is often used in rheumatoid arthritis. eHealthMe is studying from 64,791 Rituxan users. Check the latest studies of Rituxan.
What is Retinal detachment?
Retinal detachment (a disorder of the eye in which the retina peels away from its underlying layer of support tissue) is found to be associated with 714 drugs and 1,007 conditions by eHealthMe. Check the latest studies of Retinal detachment.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
64,282 people reported to have side effects when taking Rituxan.
Among them, 30 people (0.05%) have Retinal detachment.

Among these 30 people:
How long have people been on Rituxan when they have Retinal detachment? *
- < 1 month: 25.0 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 62.5 %
- 2 - 5 years: 12.5 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Retinal detachment when taking Rituxan? *
- female: 63.33 %
- male: 36.67 %
What is the age of people who have Retinal detachment when taking Rituxan? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 26.92 %
- 40-49: 3.85 %
- 50-59: 30.77 %
- 60+: 38.46 %
What are other drugs people take besides Rituxan? *
- Singulair: 10 people, 33.33%
- Zopiclone: 8 people, 26.67%
- Metformin: 8 people, 26.67%
- Amlodipine: 8 people, 26.67%
- Ventolin: 8 people, 26.67%
- Crestor: 7 people, 23.33%
- Zoloft: 7 people, 23.33%
- Synthroid: 7 people, 23.33%
- Celebrex: 6 people, 20.00%
- Valtrex: 6 people, 20.00%
What are other side effects people have besides Retinal detachment? *
- Joint Pain: 14 people, 46.67%
- Cataract (clouding of the lens inside the eye): 13 people, 43.33%
- Infusion Related Reaction: 13 people, 43.33%
- Tooth Disorder (tooth disease): 12 people, 40.00%
- Oxygen Saturation Decreased: 12 people, 40.00%
- Weight Increased: 11 people, 36.67%
- High Blood Pressure: 11 people, 36.67%
- Respiratory Rate Increased (excess breathing rate/min): 9 people, 30.00%
- Drug Ineffective: 9 people, 30.00%
- Nasopharyngitis (inflammation of the nasopharynx): 9 people, 30.00%
What are the existing conditions these people have? *
- Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 5 people, 16.67%
- Inflammation: 5 people, 16.67%
- Chronic Graft Versus Host Disease (immune cells attack the host's body cells after transplant): 5 people, 16.67%
- Urinary Retention (the inability to completely or partially empty the bladder): 3 people, 10.00%
- Pneumonia: 1 person, 3.33%
- Osteoporosis (bones weak and more likely to break): 1 person, 3.33%
- Nephrotic Syndrome (kidney disease with proteinuria, hypoalbuminemia, and oedema): 1 person, 3.33%
- Lymphoma (cancer that begins in immune system cells): 1 person, 3.33%
- Glomerulonephritis Membranous (nephritis with inflammation of the capillary loops in the renal glomeruli): 1 person, 3.33%
- Chronic Lymphocytic Leukaemia Transformation (white blood cell cancer changes in fast growing cancer in lymph node): 1 person, 3.33%
* Approximation only. Some reports may have incomplete information.
Do you take Rituxan and have Retinal detachment?
- Check whether Retinal detachment is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Rituxan:
- Rituxan (64,791 reports)
Retinal detachment treatments and more:
- Retinal detachment (11,679 reports)
How severe was Retinal detachment and when was it recovered:
Expand to all the drugs that have ingredients of rituximab:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Rituxan:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Retinal detachment:
- Retinal detachment (714 drugs)
Browse all the conditions that are associated with Retinal detachment:
- Retinal detachment (1,007 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on rituximab (the active ingredients of Rituxan) and Rituxan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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