Robinul and Orthostatic hypotension - a phase IV clinical study of FDA data

Summary:

Orthostatic hypotension is reported as a side effect among people who take Robinul (glycopyrrolate), especially for people who are female, 40-49 old, also take Zantac, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Orthostatic hypotension when taking Robinul. It is created by eHealthMe based on reports of 1,584 people who have side effects when taking Robinul from the FDA, and is updated regularly.

What is Robinul?

Robinul has active ingredients of glycopyrrolate. It is often used in hyperhidrosis. eHealthMe is studying from 1,663 Robinul users. Check the latest studies of Robinul.

What is Orthostatic hypotension?

Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up) is found to be associated with 1,228 drugs and 1,336 conditions by eHealthMe. Check the latest studies of Orthostatic hypotension.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

1,584 people reported to have side effects when taking Robinul.
Among them, 12 people (0.76%) have Orthostatic hypotension.

Could Robinul cause Orthostatic hypotension?

Among these 12 people:

What is the gender of people who have Orthostatic hypotension when taking Robinul? *

female: 66.67 %
male: 33.33 %

What is the age of people who have Orthostatic hypotension when taking Robinul? *

What are other drugs people take besides Robinul? *

What are other side effects people have besides Orthostatic hypotension? *

Diabetes: 12 people, 100.00%
Nausea (feeling of having an urge to vomit): 12 people, 100.00%
Dizziness: 12 people, 100.00%
Osteopenia (a condition where bone mineral density is lower than normal): 10 people, 83.33%
Malaise (a feeling of general discomfort or uneasiness): 9 people, 75.00%
Fatigue (feeling of tiredness): 9 people, 75.00%
Depression: 8 people, 66.67%
Fall: 8 people, 66.67%
Fever: 8 people, 66.67%
Stomatitis (inflammation of mucous membrane of mouth): 8 people, 66.67%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 7 people, 58.33%
Limb Discomfort (discomfort in leg): 1 person, 8.33%
Hypersensitivity: 1 person, 8.33%
Fibromyalgia (a long-term condition which causes pain all over the body): 1 person, 8.33%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 8.33%
Bone Disorder: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Robinul and have Orthostatic hypotension?

- Check whether Orthostatic hypotension is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Robinul:

Robinul (1,663 reports)

Browse all side effects of Robinul:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Orthostatic hypotension:

Orthostatic hypotension (1,228 drugs)

Browse all the conditions that are associated with Orthostatic hypotension:

Orthostatic hypotension (1,336 conditions)

Related publications that referenced our studies

D'souza S, Gowler V, "Glycopyrrolate‐induced respiratory arrest: an unusual side effect", Acta Anaesthesiologica Scandinavica, 2015 Mar .
D'souza S, Gowler V, "Glycopyrrolate‐induced respiratory arrest: an unusual side effect", Acta Anaesthesiologica Scandinavica, 2015 Mar .

How the study uses the data?

The study uses data from the FDA. It is based on glycopyrrolate (the active ingredients of Robinul) and Robinul (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.