Robitussin and Acute respiratory failure - a phase IV clinical study of FDA data

Summary:

Acute respiratory failure is reported as a side effect among people who take Robitussin (guaifenesin), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Lasix, and have Pain.

The phase IV clinical study analyzes which people have Acute respiratory failure when taking Robitussin. It is created by eHealthMe based on reports of 3,522 people who have side effects when taking Robitussin from the FDA, and is updated regularly.

What is Robitussin?

Robitussin has active ingredients of guaifenesin. eHealthMe is studying from 3,532 Robitussin users. Check the latest studies of Robitussin.

What is Acute respiratory failure?

Acute respiratory failure is found to be associated with 1,317 drugs and 1,650 conditions by eHealthMe. Check the latest studies of Acute respiratory failure.

On Jul, 23, 2026

3,522 people reported to have side effects when taking Robitussin.
Among them, 34 people (0.97%) have Acute respiratory failure.

Could Robitussin cause Acute respiratory failure?

Among these 34 people:

How long have people been on Robitussin when they have Acute respiratory failure? *

What is the gender of people who have Acute respiratory failure when taking Robitussin? *

female: 70.97 %
male: 29.03 %

What is the age of people who have Acute respiratory failure when taking Robitussin? *

What are other drugs people take besides Robitussin? *

What are other side effects people have besides Acute respiratory failure? *

Pneumonia: 15 people, 44.12%
Dyspnea (difficult or laboured breathing): 10 people, 29.41%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 10 people, 29.41%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 9 people, 26.47%
Sepsis (a severe blood infection that can lead to organ failure and death): 7 people, 20.59%
Wheezing (a high-pitched whistling sound made while you breath): 7 people, 20.59%
Productive Cough: 7 people, 20.59%
Hypotension (abnormally low blood pressure): 6 people, 17.65%
Fluid Overload (too much fluid in the blood): 6 people, 17.65%
Cough: 6 people, 17.65%

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 7 people, 20.59%
Pain: 7 people, 20.59%
Cough: 6 people, 17.65%
Dyspnea (difficult or laboured breathing): 5 people, 14.71%
Fever: 4 people, 11.76%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 4 people, 11.76%
Wheezing (a high-pitched whistling sound made while you breath): 3 people, 8.82%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 8.82%
Constipation: 3 people, 8.82%
Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 8.82%

* Approximation only. Some reports may have incomplete information.

Do you take Robitussin and have Acute respiratory failure?

- Check whether Acute respiratory failure is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Robitussin:

Robitussin (3,532 reports)

Browse all side effects of Robitussin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Acute respiratory failure:

Acute respiratory failure (1,317 drugs)

Browse all the conditions that are associated with Acute respiratory failure:

Acute respiratory failure (1,650 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on guaifenesin (the active ingredients of Robitussin) and Robitussin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.