Robitussin and Cardiomyopathy - a phase IV clinical study of FDA data

Summary:

Cardiomyopathy is reported as a side effect among people who take Robitussin (guaifenesin), especially for people who are female, 20-29 old, also take Lasix, and have Cryptococcosis.

The phase IV clinical study analyzes which people have Cardiomyopathy when taking Robitussin. It is created by eHealthMe based on reports of 3,522 people who have side effects when taking Robitussin from the FDA, and is updated regularly.

What is Robitussin?

Robitussin has active ingredients of guaifenesin. eHealthMe is studying from 3,532 Robitussin users. Check the latest studies of Robitussin.

What is Cardiomyopathy?

Cardiomyopathy (weakening of the heart muscle) is found to be associated with 1,254 drugs and 1,209 conditions by eHealthMe. Check the latest studies of Cardiomyopathy.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Jul, 04, 2026

3,522 people reported to have side effects when taking Robitussin.
Among them, 17 people (0.48%) have Cardiomyopathy.

Among these 17 people:

What is the gender of people who have Cardiomyopathy when taking Robitussin? *

female: 88.24 %
male: 11.76 %

What is the age of people who have Cardiomyopathy when taking Robitussin? *

What are other drugs people take besides Robitussin? *

What are other side effects people have besides Cardiomyopathy? *

Cardiac Failure Congestive: 13 people, 76.47%
Influenza Like Illness: 13 people, 76.47%
Tuberculin Test Positive: 13 people, 76.47%
Chest Pain: 12 people, 70.59%
Back Pain: 12 people, 70.59%
Presyncope: 12 people, 70.59%
Lobar Pneumonia (a form of pneumonia that affects a large and continuous area of the lobe of a lung): 12 people, 70.59%
High Blood Cholesterol: 11 people, 64.71%
Polycystic Ovary Disease (cysts in the ovaries that occurs when the follicle stops developing): 11 people, 64.71%
Renal Cell Carcinoma (a kidney cancer): 11 people, 64.71%

What are the existing conditions these people have? *

Ventricular Tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart): 1 person, 5.88%
Ventricular Extrasystoles (premature cardiac contraction): 1 person, 5.88%
Undifferentiated Connective Tissue Disease: 1 person, 5.88%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 5.88%
Pain: 1 person, 5.88%
Osteoporosis (bones weak and more likely to break): 1 person, 5.88%
Muscle Spasms (muscle contraction): 1 person, 5.88%
Joint Pain: 1 person, 5.88%
Dizziness: 1 person, 5.88%
Cryptococcosis (potentially fatal fungal disease): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Robitussin and have Cardiomyopathy?

- Check whether Cardiomyopathy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Robitussin:

Robitussin (3,532 reports)

Cardiomyopathy treatments and more:

Cardiomyopathy (22,221 reports)

Browse all side effects of Robitussin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Cardiomyopathy:

Cardiomyopathy (1,254 drugs)

Browse all the conditions that are associated with Cardiomyopathy:

Cardiomyopathy (1,209 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on guaifenesin (the active ingredients of Robitussin) and Robitussin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.