Robitussin and Staphylococcal infection - a phase IV clinical study of FDA data

Summary:

Staphylococcal infection is reported as a side effect among people who take Robitussin (guaifenesin), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Lasix, and have Swelling.

The phase IV clinical study analyzes which people have Staphylococcal infection when taking Robitussin. It is created by eHealthMe based on reports of 3,522 people who have side effects when taking Robitussin from the FDA, and is updated regularly.

What is Robitussin?

Robitussin has active ingredients of guaifenesin. eHealthMe is studying from 3,532 Robitussin users. Check the latest studies of Robitussin.

What is Staphylococcal infection?

Staphylococcal infection (an infection with staphylococcus bacteria) is found to be associated with 1,723 drugs and 1,898 conditions by eHealthMe. Check the latest studies of Staphylococcal infection.



On Jul, 14, 2026

3,522 people reported to have side effects when taking Robitussin.
Among them, 13 people (0.37%) have Staphylococcal infection.

Could Robitussin cause Staphylococcal infection?

Among these 13 people:

How long have people been on Robitussin when they have Staphylococcal infection? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Staphylococcal infection when taking Robitussin? *

  • female: 61.54 %
  • male: 38.46 %

What is the age of people who have Staphylococcal infection when taking Robitussin? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 18.18 %
  • 30-39: 0.0 %
  • 40-49: 9.09 %
  • 50-59: 0.0 %
  • 60+: 72.73 %

What are other drugs people take besides Robitussin? *

  1. Lasix: 5 people, 38.46%
  2. Phenergan: 4 people, 30.77%
  3. Neurontin: 4 people, 30.77%
  4. Lipitor: 4 people, 30.77%
  5. Colace: 4 people, 30.77%
  6. Levaquin: 3 people, 23.08%
  7. Flagyl: 3 people, 23.08%
  8. Singulair: 3 people, 23.08%
  9. Zolpidem: 3 people, 23.08%
  10. Folic Acid: 3 people, 23.08%

What are other side effects people have besides Staphylococcal infection? *

  1. Weakness: 4 people, 30.77%
  2. Swallowing Difficulty: 3 people, 23.08%
  3. Multi-Organ Failure (multisystem organ failure): 3 people, 23.08%
  4. High Blood Pressure: 3 people, 23.08%
  5. General Physical Health Deterioration (weak health status): 3 people, 23.08%
  6. Fever: 3 people, 23.08%
  7. Sinusitis (inflammation of sinus): 3 people, 23.08%
  8. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 23.08%
  9. Fatigue (feeling of tiredness): 3 people, 23.08%
  10. Urinary Tract Infection: 3 people, 23.08%

What are the existing conditions these people have? *

  1. Wheezing (a high-pitched whistling sound made while you breath): 2 people, 15.38%
  2. Pain: 2 people, 15.38%
  3. Immunodeficiency Common Variable: 2 people, 15.38%
  4. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 15.38%
  5. Dyspnea (difficult or laboured breathing): 2 people, 15.38%
  6. Constipation: 2 people, 15.38%
  7. Gastric Ulcer (stomach ulcer): 2 people, 15.38%
  8. Sleep Disorder: 2 people, 15.38%
  9. Swelling: 2 people, 15.38%
  10. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Robitussin and have Staphylococcal infection?

- Check whether Staphylococcal infection is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Robitussin:

Staphylococcal infection treatments and more:

How severe was Staphylococcal infection and when was it recovered:

Expand to all the drugs that have ingredients of guaifenesin:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Robitussin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Staphylococcal infection:

Browse all the conditions that are associated with Staphylococcal infection:


How the study uses the data?

The study uses data from the FDA. It is based on guaifenesin (the active ingredients of Robitussin) and Robitussin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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