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Robitussin and Toothaches - a phase IV clinical study of FDA data

Summary:

Toothaches is reported as a side effect among people who take Robitussin (guaifenesin), especially for people who are female, 50-59 old, also take Vitamin B12, and have Cough.

The phase IV clinical study analyzes which people have Toothaches when taking Robitussin. It is created by eHealthMe based on reports of 3,522 people who have side effects when taking Robitussin from the FDA, and is updated regularly.

What is Robitussin?

Robitussin has active ingredients of guaifenesin. eHealthMe is studying from 3,532 Robitussin users. Check the latest studies of Robitussin.

What is Toothaches?

Toothaches (tooth pain) is found to be associated with 1,321 drugs and 1,606 conditions by eHealthMe. Check the latest studies of Toothaches.

On Aug, 06, 2026

3,522 people reported to have side effects when taking Robitussin.
Among them, 11 people (0.31%) have Toothaches.

Could Robitussin cause Toothaches?

Among these 11 people:

What is the gender of people who have Toothaches when taking Robitussin? *

  • female: 80 %
  • male: 20 %

What is the age of people who have Toothaches when taking Robitussin? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 10 %
  • 50-59: 80 %
  • 60+: 10 %

What are other drugs people take besides Robitussin? *

  1. Lipitor: 10 people, 90.91%
  2. Vitamin B12: 10 people, 90.91%
  3. Metformin: 8 people, 72.73%
  4. Movantik: 8 people, 72.73%
  5. Oxycodone: 8 people, 72.73%
  6. Crestor: 8 people, 72.73%
  7. Sertraline: 8 people, 72.73%
  8. Relistor: 8 people, 72.73%
  9. Percocet: 7 people, 63.64%
  10. Zejula: 5 people, 45.45%

What are other side effects people have besides Toothaches? *

  1. Dry Mouth: 9 people, 81.82%
  2. Pain: 9 people, 81.82%
  3. Emotional Distress: 9 people, 81.82%
  4. Weight Decreased: 8 people, 72.73%
  5. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 72.73%
  6. Joint Pain: 8 people, 72.73%
  7. Itching: 8 people, 72.73%
  8. Insomnia (sleeplessness): 8 people, 72.73%
  9. Weakness: 8 people, 72.73%
  10. Indigestion: 8 people, 72.73%

What are the existing conditions these people have? *

  1. Neoplasm Malignant (cancer tumour): 8 people, 72.73%
  2. Malignant Peritoneal Neoplasm (cancer tumour of peritoneum): 8 people, 72.73%
  3. Cough: 8 people, 72.73%
  4. Ovarian Cancer (cancer of ovary): 5 people, 45.45%
  5. Joint Pain: 2 people, 18.18%
  6. Multiple Myeloma (cancer of the plasma cells): 1 person, 9.09%
  7. Hiv Infection: 1 person, 9.09%
  8. Asthma: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Robitussin and have Toothaches?

- Check whether Toothaches is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Robitussin:

Toothaches treatments and more:

How severe was Toothaches and when was it recovered:

Expand to all the drugs that have ingredients of guaifenesin:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Robitussin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Toothaches:

Browse all the conditions that are associated with Toothaches:

How the study uses the data?

The study uses data from the FDA. It is based on guaifenesin (the active ingredients of Robitussin) and Robitussin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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