Rocephin and Calcinosis - a phase IV clinical study of FDA data

Summary:

Calcinosis is reported as a side effect among people who take Rocephin (ceftriaxone sodium), especially for people who are male, 50-59 old, also take Zofran, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Calcinosis when taking Rocephin. It is created by eHealthMe based on reports of 15,458 people who have side effects when taking Rocephin from the FDA, and is updated regularly.

What is Rocephin?

Rocephin has active ingredients of ceftriaxone sodium. It is often used in infection. eHealthMe is studying from 15,665 Rocephin users. Check the latest studies of Rocephin.

What is Calcinosis?

Calcinosis (calcium deposits in any soft tissue) is found to be associated with 422 drugs and 859 conditions by eHealthMe. Check the latest studies of Calcinosis.

On Jul, 12, 2026

15,458 people reported to have side effects when taking Rocephin.
Among them, 13 people (0.08%) have Calcinosis.

Among these 13 people:

What is the gender of people who have Calcinosis when taking Rocephin? *

female: 30.77 %
male: 69.23 %

What is the age of people who have Calcinosis when taking Rocephin? *

What are other drugs people take besides Rocephin? *

What are other side effects people have besides Calcinosis? *

Joint Pain: 11 people, 84.62%
Oedema Peripheral (superficial swelling): 10 people, 76.92%
Stress And Anxiety: 9 people, 69.23%
Fatigue (feeling of tiredness): 8 people, 61.54%
Pollakiuria (abnormally frequent passage of relatively small quantities or urine): 8 people, 61.54%
Cellulitis (infection under the skin): 8 people, 61.54%
Jugular Vein Thrombosis (clot in jugular vein): 7 people, 53.85%
Drug Dependence: 6 people, 46.15%
Drug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation): 6 people, 46.15%
Coughing Up Blood: 6 people, 46.15%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 2 people, 15.38%
Thyroid Diseases: 1 person, 7.69%
Sinusitis (inflammation of sinus): 1 person, 7.69%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 1 person, 7.69%
Quit Smoking: 1 person, 7.69%
Post-Traumatic Stress Disorder: 1 person, 7.69%
Hypokalemia (low potassium): 1 person, 7.69%
Grand Mal Convulsion (a type of generalized seizure that affects the entire brain): 1 person, 7.69%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 7.69%
Erysipelas (bacterial skin infection): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Rocephin and have Calcinosis?

- Check whether Calcinosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Rocephin:

Rocephin (15,665 reports)

Calcinosis treatments and more:

Calcinosis (3,651 reports)

Browse all side effects of Rocephin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Calcinosis:

Calcinosis (422 drugs)

Browse all the conditions that are associated with Calcinosis:

Calcinosis (859 conditions)

Related publications that referenced our studies

Agrawal SR, Rajput A, Jain AP, "Leukocytoclastic vasculitis and acute allergic interstitial nephritis following ceftriaxone exposure", Journal of pharmacology & pharmacotherapeutics, 2014 Jan .
Agrawal SR, Rajput A, Jain AP, "Leukocytoclastic vasculitis and acute allergic interstitial nephritis following ceftriaxone exposure", Journal of pharmacology & pharmacotherapeutics, 2014 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on ceftriaxone sodium (the active ingredients of Rocephin) and Rocephin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.