Rocephin and Mitral valve disease - a phase IV clinical study of FDA data

Summary:

Mitral valve disease is reported as a side effect among people who take Rocephin (ceftriaxone sodium), especially for people who are female, 60+ old, also take Aredia, and have Urticaria.

The phase IV clinical study analyzes which people have Mitral valve disease when taking Rocephin. It is created by eHealthMe based on reports of 15,458 people who have side effects when taking Rocephin from the FDA, and is updated regularly.

What is Rocephin?

Rocephin has active ingredients of ceftriaxone sodium. It is often used in infection. eHealthMe is studying from 15,665 Rocephin users. Check the latest studies of Rocephin.

What is Mitral valve disease?

Mitral valve disease (disease of mitral valve of heart) is found to be associated with 458 drugs and 456 conditions by eHealthMe. Check the latest studies of Mitral valve disease.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

15,458 people reported to have side effects when taking Rocephin.
Among them, 21 people (0.14%) have Mitral valve disease.

Could Rocephin cause Mitral valve disease?

Among these 21 people:

What is the gender of people who have Mitral valve disease when taking Rocephin? *

female: 80.95 %
male: 19.05 %

What is the age of people who have Mitral valve disease when taking Rocephin? *

What are other drugs people take besides Rocephin? *

What are other side effects people have besides Mitral valve disease? *

Diarrhea: 18 people, 85.71%
Weight Decreased: 17 people, 80.95%
Weakness: 17 people, 80.95%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 17 people, 80.95%
Stress And Anxiety: 17 people, 80.95%
Pain: 17 people, 80.95%
Injury: 15 people, 71.43%
Musculoskeletal Chest Pain (pain in chest muscle or nerve or bones): 15 people, 71.43%
Dizziness: 15 people, 71.43%
Toothaches (tooth pain): 15 people, 71.43%

What are the existing conditions these people have? *

Urticaria (rash of round, red welts on the skin that itch intensely): 5 people, 23.81%
Nocardia Infection (a bacterial infection that usually starts in the lungs. it may spread to other organ systems): 2 people, 9.52%
Hiv Infection: 1 person, 4.76%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 1 person, 4.76%
Acne (skin problems that cause pimples): 1 person, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Rocephin and have Mitral valve disease?

- Check whether Mitral valve disease is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Rocephin:

Rocephin (15,665 reports)

Browse all side effects of Rocephin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Mitral valve disease:

Mitral valve disease (458 drugs)

Browse all the conditions that are associated with Mitral valve disease:

Mitral valve disease (456 conditions)

Related publications that referenced our studies

Agrawal SR, Rajput A, Jain AP, "Leukocytoclastic vasculitis and acute allergic interstitial nephritis following ceftriaxone exposure", Journal of pharmacology & pharmacotherapeutics, 2014 Jan .
Agrawal SR, Rajput A, Jain AP, "Leukocytoclastic vasculitis and acute allergic interstitial nephritis following ceftriaxone exposure", Journal of pharmacology & pharmacotherapeutics, 2014 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on ceftriaxone sodium (the active ingredients of Rocephin) and Rocephin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.