Roflumilast and Sinus pain - a phase IV clinical study of FDA data

Summary:

Sinus pain is reported as a side effect among people who take Roflumilast (roflumilast), especially for people who are male, 60+ old, also take Symbicort, and have Asthma.

The phase IV clinical study analyzes which people have Sinus pain when taking Roflumilast. It is created by eHealthMe based on reports of 2,239 people who have side effects when taking Roflumilast from the FDA, and is updated regularly.

What is Roflumilast?

Roflumilast has active ingredients of roflumilast. eHealthMe is studying from 2,247 Roflumilast users. Check the latest studies of Roflumilast.

What is Sinus pain?

Sinus pain is found to be associated with 367 drugs and 318 conditions by eHealthMe. Check the latest studies of Sinus pain.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 29, 2026

2,239 people reported to have side effects when taking Roflumilast.
Among them, 15 people (0.67%) have Sinus pain.

Among these 15 people:

What is the gender of people who have Sinus pain when taking Roflumilast? *

female: 0.0 %
male: 100 %

What is the age of people who have Sinus pain when taking Roflumilast? *

What are other drugs people take besides Roflumilast? *

What are other side effects people have besides Sinus pain? *

Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 15 people, 100.00%
Nasal Obstruction (blockage of nose): 15 people, 100.00%
Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection): 15 people, 100.00%
Chest Pain: 15 people, 100.00%
Cough: 15 people, 100.00%
Drug Ineffective: 15 people, 100.00%
Dyspnea (difficult or laboured breathing): 15 people, 100.00%
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs): 15 people, 100.00%
Lung Consolidation (a condition whereby the lung tissues solidify because of the accumulation of solid and liquid material in the air spaces): 15 people, 100.00%
Mycobacterium Avium Complex Infection: 15 people, 100.00%

What are the existing conditions these people have? *

Asthma: 2 people, 13.33%

* Approximation only. Some reports may have incomplete information.

Do you take Roflumilast and have Sinus pain?

- Check whether Sinus pain is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Roflumilast:

Roflumilast (2,247 reports)

Sinus pain treatments and more:

Sinus pain (3,575 reports)

Browse all side effects of Roflumilast:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sinus pain:

Sinus pain (367 drugs)

Browse all the conditions that are associated with Sinus pain:

Sinus pain (318 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on roflumilast (the active ingredients of Roflumilast) and Roflumilast (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.