Rogaine and Dark circles under eyes - a phase IV clinical study of FDA data

Summary:

Dark circles under eyes is reported as a side effect among people who take Rogaine (minoxidil), especially for people who are female, 50-59 old, have been taking the drug for 1 - 6 months also take Boron, and have High blood pressure.

The phase IV clinical study analyzes which people have Dark circles under eyes when taking Rogaine. It is created by eHealthMe based on reports of 33,950 people who have side effects when taking Rogaine from the FDA, and is updated regularly.

What is Rogaine?

Rogaine has active ingredients of minoxidil. It is often used in hair loss. eHealthMe is studying from 34,083 Rogaine users. Check the latest studies of Rogaine.

What is Dark circles under eyes?

Dark circles under eyes is found to be associated with 155 drugs and 649 conditions by eHealthMe. Check the latest studies of Dark circles under eyes.

On Jul, 04, 2026

33,950 people reported to have side effects when taking Rogaine.
Among them, 28 people (0.08%) have Dark circles under eyes.

Could Rogaine cause Dark circles under eyes?

Among these 28 people:

How long have people been on Rogaine when they have Dark circles under eyes? *

What is the gender of people who have Dark circles under eyes when taking Rogaine? *

female: 58.33 %
male: 41.67 %

What is the age of people who have Dark circles under eyes when taking Rogaine? *

What are other drugs people take besides Rogaine? *

What are other side effects people have besides Dark circles under eyes? *

Skin Wrinkling (wrinkle on skin): 11 people, 39.29%
Eye Swelling: 6 people, 21.43%
Headache (pain in head): 2 people, 7.14%
Rashes (redness): 2 people, 7.14%
Suicidal Ideation: 2 people, 7.14%
Erection Problems: 2 people, 7.14%
Itching: 2 people, 7.14%
Libido Decreased (loss of interest in sex): 2 people, 7.14%
Dry Eyes (lack of adequate tears): 2 people, 7.14%
Overdose: 2 people, 7.14%

What are the existing conditions these people have? *

High Blood Pressure: 3 people, 10.71%
Skin Disorder (skin disease): 1 person, 3.57%
Nail Disorder (disease of nail): 1 person, 3.57%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 3.57%
High Blood Cholesterol: 1 person, 3.57%
Hair Disorder: 1 person, 3.57%
Cardiac Disorder: 1 person, 3.57%
Androgenetic Alopecia (common form of hair loss): 1 person, 3.57%

* Approximation only. Some reports may have incomplete information.

Do you take Rogaine and have Dark circles under eyes?

- Check whether Dark circles under eyes is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Rogaine:

Rogaine (34,083 reports)

Browse all side effects of Rogaine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Dark circles under eyes:

Dark circles under eyes (155 drugs)

Browse all the conditions that are associated with Dark circles under eyes:

Dark circles under eyes (649 conditions)

Related publications that referenced our studies

Dubrey SW, VanGriethuysen J, Edwards CM, "A hairy fall: syncope resulting from topical application of minoxidil", BMJ case reports, 2015 Sep .
Dubrey SW, VanGriethuysen J, Edwards CM, "A hairy fall: syncope resulting from topical application of minoxidil", BMJ case reports, 2015 Sep .

How the study uses the data?

The study uses data from the FDA. It is based on minoxidil (the active ingredients of Rogaine) and Rogaine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.