Roxanol and Diarrhea - a phase IV clinical study of FDA data

Summary:

Diarrhea is reported as a side effect among people who take Roxanol (morphine sulfate), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Zometa, and have Metastases to bone.

The phase IV clinical study analyzes which people have Diarrhea when taking Roxanol. It is created by eHealthMe based on reports of 804 people who have side effects when taking Roxanol from the FDA, and is updated regularly.

What is Roxanol?

Roxanol has active ingredients of morphine sulfate. eHealthMe is studying from 807 Roxanol users. Check the latest studies of Roxanol.

What is Diarrhea?

Diarrhea is found to be associated with 3,727 drugs and 5,754 conditions by eHealthMe. Check the latest studies of Diarrhea.



On Aug, 06, 2026

804 people reported to have side effects when taking Roxanol.
Among them, 78 people (9.7%) have Diarrhea.

Could Roxanol cause Diarrhea?

Among these 78 people:

How long have people been on Roxanol when they have Diarrhea? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Diarrhea when taking Roxanol? *

  • female: 47.37 %
  • male: 52.63 %

What is the age of people who have Diarrhea when taking Roxanol? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 1.43 %
  • 30-39: 1.43 %
  • 40-49: 34.29 %
  • 50-59: 17.14 %
  • 60+: 45.71 %

What are other drugs people take besides Roxanol? *

  1. Zometa: 55 people, 70.51%
  2. Zofran: 37 people, 47.44%
  3. Ambien: 35 people, 44.87%
  4. Decadron: 29 people, 37.18%
  5. Aredia: 29 people, 37.18%
  6. Levaquin: 26 people, 33.33%
  7. Celebrex: 24 people, 30.77%
  8. Dexamethasone: 24 people, 30.77%
  9. Colace: 23 people, 29.49%
  10. Vicodin: 23 people, 29.49%

What are other side effects people have besides Diarrhea? *

  1. Pain: 51 people, 65.38%
  2. Nausea (feeling of having an urge to vomit): 50 people, 64.10%
  3. Stress And Anxiety: 50 people, 64.10%
  4. Fatigue (feeling of tiredness): 44 people, 56.41%
  5. Osteonecrosis Of Jaw (death of bone of jaw): 42 people, 53.85%
  6. Back Pain: 42 people, 53.85%
  7. Osteomyelitis (infection of bone): 38 people, 48.72%
  8. Joint Pain: 38 people, 48.72%
  9. Depression: 38 people, 48.72%
  10. Bone Disorder: 37 people, 47.44%

What are the existing conditions these people have? *

  1. Metastases To Bone (cancer spreads to bone): 25 people, 32.05%
  2. Pain: 24 people, 30.77%
  3. Breast Cancer: 14 people, 17.95%
  4. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 10 people, 12.82%
  5. Metastatic Renal Cell Carcinoma (spreadable kidney cell tumour): 10 people, 12.82%
  6. Bone Density Decreased: 10 people, 12.82%
  7. Multiple Myeloma (cancer of the plasma cells): 4 people, 5.13%
  8. Stress And Anxiety: 4 people, 5.13%
  9. Pancreatic Carcinoma (pancreatic cancer): 4 people, 5.13%
  10. Nausea (feeling of having an urge to vomit): 4 people, 5.13%

* Approximation only. Some reports may have incomplete information.

Do you take Roxanol and have Diarrhea?

- Check whether Diarrhea is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Roxanol:

Diarrhea treatments and more:

How severe was Diarrhea and when was it recovered:

Expand to all the drugs that have ingredients of morphine sulfate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Roxanol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Diarrhea:

Browse all the conditions that are associated with Diarrhea:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on morphine sulfate (the active ingredients of Roxanol) and Roxanol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: