Roxicet and Bruxism - a phase IV clinical study of FDA data

Summary:

Bruxism is reported as a side effect among people who take Roxicet (acetaminophen; oxycodone hydrochloride), especially for people who are male, 60+ old, also take Ambien, and have Lung cancer metastatic.

The phase IV clinical study analyzes which people have Bruxism when taking Roxicet. It is created by eHealthMe based on reports of 2,147 people who have side effects when taking Roxicet from the FDA, and is updated regularly.

What is Roxicet?

Roxicet has active ingredients of acetaminophen; oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 2,254 Roxicet users. Check the latest studies of Roxicet.

What is Bruxism?

Bruxism (habitual grinding of the teeth, typically during sleep) is found to be associated with 590 drugs and 983 conditions by eHealthMe. Check the latest studies of Bruxism.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Jul, 28, 2026

2,147 people reported to have side effects when taking Roxicet.
Among them, 32 people (1.49%) have Bruxism.

Among these 32 people:

What is the gender of people who have Bruxism when taking Roxicet? *

female: 50 %
male: 50 %

What is the age of people who have Bruxism when taking Roxicet? *

What are other drugs people take besides Roxicet? *

What are other side effects people have besides Bruxism? *

Mastication Disorder (disease of chewing food): 28 people, 87.50%
Periodontal Disease (disease that attacks the gum and bone and around the teeth): 27 people, 84.38%
Stress And Anxiety: 27 people, 84.38%
Bone Disorder: 27 people, 84.38%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 23 people, 71.88%
Pain In Jaw: 23 people, 71.88%
Hypoaesthesia (reduced sense of touch or sensation): 23 people, 71.88%
Anaemia (lack of blood): 21 people, 65.62%
Dizziness: 18 people, 56.25%
Deformity (disfigurement): 18 people, 56.25%

What are the existing conditions these people have? *

Neoplasm Malignant (cancer tumour): 15 people, 46.88%
Lung Cancer Metastatic (lung cancer spreads to other parts): 15 people, 46.88%
Metastases To Bone (cancer spreads to bone): 12 people, 37.50%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 12.50%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 person, 3.12%
Diabetic Gastroparesis (paralysis of the muscles of the stomach caused by diabetes): 1 person, 3.12%

* Approximation only. Some reports may have incomplete information.

Do you take Roxicet and have Bruxism?

- Check whether Bruxism is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Roxicet:

Roxicet (2,254 reports)

Bruxism treatments and more:

Bruxism (7,187 reports)

How severe was Bruxism and when was it recovered:

Bruxism in Roxicet

Expand to all the drugs that have ingredients of acetaminophen; oxycodone hydrochloride:

Bruxism and drugs with ingredients of acetaminophen; oxycodone hydrochloride (113 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Roxicet:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bruxism:

Bruxism (590 drugs)

Browse all the conditions that are associated with Bruxism:

Bruxism (983 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; oxycodone hydrochloride (the active ingredients of Roxicet) and Roxicet (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.