Roxicet and Ddd - a phase IV clinical study of FDA data

Summary:

Ddd is reported as a side effect among people who take Roxicet (acetaminophen; oxycodone hydrochloride), especially for people who are male, 60+ old, have been taking the drug for 1 - 2 years also take Zometa, and have Bone density abnormal.

The phase IV clinical study analyzes which people have Ddd when taking Roxicet. It is created by eHealthMe based on reports of 2,147 people who have side effects when taking Roxicet from the FDA, and is updated regularly.

What is Roxicet?

Roxicet has active ingredients of acetaminophen; oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 2,254 Roxicet users. Check the latest studies of Roxicet.

What is Ddd?

Ddd is found to be associated with 1,354 drugs and 1,417 conditions by eHealthMe. Check the latest studies of Ddd.



On Apr, 06, 2026

2,147 people reported to have side effects when taking Roxicet.
Among them, 50 people (2.33%) have Ddd.

Could Roxicet cause Ddd?

Among these 50 people:

How long have people been on Roxicet when they have Ddd? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 100 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Ddd when taking Roxicet? *

  • female: 30.61 %
  • male: 69.39 %

What is the age of people who have Ddd when taking Roxicet? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 4.65 %
  • 50-59: 27.91 %
  • 60+: 67.44 %

What are other drugs people take besides Roxicet? *

  1. Zometa: 36 people, 72.00%
  2. Ambien: 31 people, 62.00%
  3. Oxycontin: 27 people, 54.00%
  4. Lipitor: 25 people, 50.00%
  5. Percocet: 22 people, 44.00%
  6. Aspirin: 22 people, 44.00%
  7. Ibuprofen: 21 people, 42.00%
  8. Amoxicillin: 20 people, 40.00%
  9. Vicodin: 18 people, 36.00%
  10. Lupron: 18 people, 36.00%

What are other side effects people have besides Ddd? *

  1. Osteonecrosis Of Jaw (death of bone of jaw): 34 people, 68.00%
  2. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 34 people, 68.00%
  3. Hypoaesthesia (reduced sense of touch or sensation): 33 people, 66.00%
  4. Stress And Anxiety: 32 people, 64.00%
  5. Injury: 31 people, 62.00%
  6. Pain In Extremity: 29 people, 58.00%
  7. Fatigue (feeling of tiredness): 27 people, 54.00%
  8. Chest Pain: 26 people, 52.00%
  9. Depression: 25 people, 50.00%
  10. Renal Cyst (kidney cyst): 24 people, 48.00%

What are the existing conditions these people have? *

  1. Prostate Cancer: 9 people, 18.00%
  2. Multiple Myeloma (cancer of the plasma cells): 9 people, 18.00%
  3. Bone Density Abnormal: 9 people, 18.00%
  4. Resorption Bone Increased: 6 people, 12.00%
  5. Prostate Cancer Metastatic: 6 people, 12.00%
  6. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 6.00%
  7. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 4.00%
  8. Stress And Anxiety: 1 person, 2.00%
  9. Sleep Disorder: 1 person, 2.00%
  10. Neoplasm Malignant (cancer tumour): 1 person, 2.00%

* Approximation only. Some reports may have incomplete information.

Do you take Roxicet and have Ddd?

- Check whether Ddd is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Roxicet:

Ddd treatments and more:

  • Ddd (19,910 reports)

How severe was Ddd and when was it recovered:

Expand to all the drugs that have ingredients of acetaminophen; oxycodone hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Roxicet:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Ddd:

  • Ddd (1,354 drugs)

Browse all the conditions that are associated with Ddd:

  • Ddd (1,417 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; oxycodone hydrochloride (the active ingredients of Roxicet) and Roxicet (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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