Roxicodone and Sciatica - a phase IV clinical study of FDA data

Summary:

Sciatica is reported as a side effect among people who take Roxicodone (oxycodone hydrochloride), especially for people who are male, 50-59 old, have been taking the drug for 2 - 5 years also take Vitamin D3, and have Back pain.

The phase IV clinical study analyzes which people have Sciatica when taking Roxicodone. It is created by eHealthMe based on reports of 19,861 people who have side effects when taking Roxicodone from the FDA, and is updated regularly.

What is Roxicodone?

Roxicodone has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 20,099 Roxicodone users. Check the latest studies of Roxicodone.

What is Sciatica?

Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve) is found to be associated with 1,146 drugs and 1,427 conditions by eHealthMe. Check the latest studies of Sciatica.

On Mar, 01, 2026

19,861 people reported to have side effects when taking Roxicodone.
Among them, 9 people (0.05%) have Sciatica.

Among these 9 people:

How long have people been on Roxicodone when they have Sciatica? *

What is the gender of people who have Sciatica when taking Roxicodone? *

female: 44.44 %
male: 55.56 %

What is the age of people who have Sciatica when taking Roxicodone? *

What are other drugs people take besides Roxicodone? *

Vitamin D3: 4 people, 44.44%
Hydrocodone Bitartrate And Acetaminophen: 3 people, 33.33%
Lexapro: 3 people, 33.33%
Oxycontin: 3 people, 33.33%
Zyrtec: 2 people, 22.22%
Pepcid Ac: 2 people, 22.22%
Advair Hfa: 2 people, 22.22%
Cymbalta: 2 people, 22.22%
Motrin: 2 people, 22.22%
Adderall: 2 people, 22.22%

What are other side effects people have besides Sciatica? *

Drug Dependence: 5 people, 55.56%
Overdose: 4 people, 44.44%
Back Pain: 4 people, 44.44%
Fatigue (feeling of tiredness): 3 people, 33.33%
Joint Pain: 3 people, 33.33%
Spinal Osteoarthritis (joint cartilage loss in spine): 3 people, 33.33%
Drug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation): 3 people, 33.33%
Dyspnea (difficult or laboured breathing): 3 people, 33.33%
Heart Rate Increased: 2 people, 22.22%
Drug Abuse: 2 people, 22.22%

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 22.22%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 22.22%
Back Pain: 2 people, 22.22%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 11.11%
Procedural Pain: 1 person, 11.11%
Oestrogen Receptor Assay Positive: 1 person, 11.11%
Nausea And Vomiting: 1 person, 11.11%
Nausea (feeling of having an urge to vomit): 1 person, 11.11%
Mood Swings (an extreme or rapid change in mood): 1 person, 11.11%
Joint Pain: 1 person, 11.11%

* Approximation only. Some reports may have incomplete information.

Do you take Roxicodone and have Sciatica?

- Check whether Sciatica is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Roxicodone:

Roxicodone (20,099 reports)

Sciatica treatments and more:

Sciatica (28,509 reports)

Browse all side effects of Roxicodone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sciatica:

Sciatica (1,146 drugs)

Browse all the conditions that are associated with Sciatica:

Sciatica (1,427 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on oxycodone hydrochloride (the active ingredients of Roxicodone) and Roxicodone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.