Rozerem and Flushing - a phase IV clinical study of FDA data

Summary:

Flushing is reported as a side effect among people who take Rozerem (ramelteon), especially for people who are male, 30-39 old, have been taking the drug for < 1 month also take Allegra, and have Bipolar ii disorder.

The phase IV clinical study analyzes which people have Flushing when taking Rozerem. It is created by eHealthMe based on reports of 7,343 people who have side effects when taking Rozerem from the FDA, and is updated regularly.

What is Rozerem?

Rozerem has active ingredients of ramelteon. It is often used in insomnia. eHealthMe is studying from 7,539 Rozerem users. Check the latest studies of Rozerem.

What is Flushing?

Flushing (the warm, red condition of human skin) is found to be associated with 2,032 drugs and 2,916 conditions by eHealthMe. Check the latest studies of Flushing.

On Jul, 22, 2026

7,343 people reported to have side effects when taking Rozerem.
Among them, 13 people (0.18%) have Flushing.

Among these 13 people:

How long have people been on Rozerem when they have Flushing? *

What is the gender of people who have Flushing when taking Rozerem? *

female: 46.15 %
male: 53.85 %

What is the age of people who have Flushing when taking Rozerem? *

What are other drugs people take besides Rozerem? *

Tecfidera: 2 people, 15.38%
Lisinopril: 2 people, 15.38%
Cefazolin Sodium: 2 people, 15.38%
Simvastatin: 2 people, 15.38%
Melatonin: 2 people, 15.38%
Meclizine: 2 people, 15.38%
Vicodin: 2 people, 15.38%
Promazine Hydrochloride: 2 people, 15.38%
Lamictal: 2 people, 15.38%
Allegra: 2 people, 15.38%

What are other side effects people have besides Flushing? *

Rashes (redness): 5 people, 38.46%
Depressed Level Of Consciousness: 2 people, 15.38%
Fever: 2 people, 15.38%
Diarrhea: 2 people, 15.38%
Depression: 2 people, 15.38%
Pain: 2 people, 15.38%
Face Oedema (swelling of face): 2 people, 15.38%
Fainting (loss of consciousness and postural tone): 2 people, 15.38%
Fatigue (feeling of tiredness): 2 people, 15.38%
Blood Creatine Phosphokinase Increased: 2 people, 15.38%

What are the existing conditions these people have? *

Bipolar Ii Disorder (characterized by at least one episode of hypomania and at least one episode of major depression): 2 people, 15.38%
Stress And Anxiety: 1 person, 7.69%
High Blood Cholesterol: 1 person, 7.69%
Bronchitis Chronic (inflammation of the mucous membrane in the bronchial tubes- chronic): 1 person, 7.69%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 7.69%
Constipation: 1 person, 7.69%
Dizziness: 1 person, 7.69%
Gastroenteritis Eosinophilic (white blood cell deposits in tissue of stomach or intestine with infection): 1 person, 7.69%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 7.69%
Hidradenitis (chronic disease of a type of sweat gland): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Rozerem and have Flushing?

- Check whether Flushing is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Rozerem:

Rozerem (7,539 reports)

Flushing treatments and more:

Flushing (117,676 reports)

Browse all side effects of Rozerem:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Flushing:

Flushing (2,032 drugs)

Browse all the conditions that are associated with Flushing:

Flushing (2,916 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ramelteon (the active ingredients of Rozerem) and Rozerem (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.