Rufen and Rashes - a phase IV clinical study of FDA data

Summary:

Rashes is reported as a side effect among people who take Rufen (ibuprofen), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Nexavar, and have Hepatocellular carcinoma.

The phase IV clinical study analyzes which people have Rashes when taking Rufen. It is created by eHealthMe based on reports of 190 people who have side effects when taking Rufen from the FDA, and is updated regularly.

What is Rufen?

Rufen has active ingredients of ibuprofen. eHealthMe is studying from 205 Rufen users. Check the latest studies of Rufen.

What is Rashes?

Rashes (redness) is found to be associated with 3,715 drugs and 6,215 conditions by eHealthMe. Check the latest studies of Rashes.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

190 people reported to have side effects when taking Rufen.
Among them, 17 people (8.95%) have Rashes.

Among these 17 people:

How long have people been on Rufen when they have Rashes? *

What is the gender of people who have Rashes when taking Rufen? *

female: 62.5 %
male: 37.5 %

What is the age of people who have Rashes when taking Rufen? *

What are other drugs people take besides Rufen? *

What are other side effects people have besides Rashes? *

Constipation: 8 people, 47.06%
Itching: 7 people, 41.18%
High Blood Pressure: 6 people, 35.29%
Muscle Spasms (muscle contraction): 6 people, 35.29%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 6 people, 35.29%
Diarrhea: 6 people, 35.29%
Palmar-Plantar Erythrodysaesthesia Syndrome (hand-foot syndrome): 6 people, 35.29%
The Flu (the flu is caused by an influenza virus): 6 people, 35.29%
Blood Glucose Increased: 5 people, 29.41%
Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 5 people, 29.41%

What are the existing conditions these people have? *

Hepatocellular Carcinoma (liver cancer): 5 people, 29.41%
High Blood Pressure: 4 people, 23.53%
Abdominal Pain Upper: 2 people, 11.76%
Joint Pain: 2 people, 11.76%
Adult T-Cell Lymphoma/leukaemia (cancer of the immune system's own t-cells): 1 person, 5.88%
Arrhythmias (irregular heartbeat): 1 person, 5.88%
Carotid Artery Stenosis (narrowing of carotid artery): 1 person, 5.88%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 1 person, 5.88%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 1 person, 5.88%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Rufen and have Rashes?

- Check whether Rashes is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Rufen:

Rufen (205 reports)

Rashes treatments and more:

Rashes (702,909 reports)

Browse all side effects of Rufen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Rashes:

Rashes (3,715 drugs)

Browse all the conditions that are associated with Rashes:

Rashes (6,215 conditions)

Related publications that referenced our studies

Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .
Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .

How the study uses the data?

The study uses data from the FDA. It is based on ibuprofen (the active ingredients of Rufen) and Rufen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.