Rydapt and Headache - a phase IV clinical study of FDA data

Summary:

Headache is reported as a side effect among people who take Rydapt (midostaurin), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Cytarabine, and have Acute myeloid leukaemia.

The phase IV clinical study analyzes which people have Headache when taking Rydapt. It is created by eHealthMe based on reports of 2,005 people who have side effects when taking Rydapt from the FDA, and is updated regularly.

What is Rydapt?

Rydapt has active ingredients of midostaurin. eHealthMe is studying from 2,005 Rydapt users. Check the latest studies of Rydapt.

What is Headache?

Headache (pain in head) is found to be associated with 3,753 drugs and 5,772 conditions by eHealthMe. Check the latest studies of Headache.

On Aug, 05, 2026

2,005 people reported to have side effects when taking Rydapt.
Among them, 34 people (1.7%) have Headache.

Among these 34 people:

How long have people been on Rydapt when they have Headache? *

What is the gender of people who have Headache when taking Rydapt? *

female: 42.42 %
male: 57.58 %

What is the age of people who have Headache when taking Rydapt? *

What are other drugs people take besides Rydapt? *

Cytarabine: 8 people, 23.53%
Nexium: 4 people, 11.76%
Daunorubicin Hydrochloride: 4 people, 11.76%
Ondansetron: 4 people, 11.76%
Levofloxacin: 3 people, 8.82%
Aloxi: 3 people, 8.82%
Dexamethasone: 3 people, 8.82%
Exjade: 3 people, 8.82%
Allopurinol: 3 people, 8.82%
Noxafil: 3 people, 8.82%

What are other side effects people have besides Headache? *

Nausea (feeling of having an urge to vomit): 16 people, 47.06%
Fever: 11 people, 32.35%
Diarrhea: 9 people, 26.47%
Thrombocytopenia (decrease of platelets in blood): 8 people, 23.53%
Insomnia (sleeplessness): 7 people, 20.59%
Nausea And Vomiting: 7 people, 20.59%
Dyspnea (difficult or laboured breathing): 7 people, 20.59%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 7 people, 20.59%
Fatigue (feeling of tiredness): 7 people, 20.59%
Abdominal Pain: 6 people, 17.65%

What are the existing conditions these people have? *

Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 18 people, 52.94%
Urticaria Pigmentosa (skin disease that produces patches of darker skin (lesions) and very bad itching): 5 people, 14.71%
Systemic Mastocytosis (a condition caused by the accumulation of mast cells in more than one part of the body): 5 people, 14.71%
Joint Pain: 3 people, 8.82%
High Blood Cholesterol: 3 people, 8.82%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 2 people, 5.88%
Nausea (feeling of having an urge to vomit): 1 person, 2.94%
Hypersensitivity: 1 person, 2.94%
Blood Triglycerides Decreased: 1 person, 2.94%

* Approximation only. Some reports may have incomplete information.

Do you take Rydapt and have Headache?

- Check whether Headache is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Rydapt:

Rydapt (2,005 reports)

Headache treatments and more:

Headache (756,642 reports)

Browse all side effects of Rydapt:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Headache:

Headache (3,753 drugs)

Browse all the conditions that are associated with Headache:

Headache (5,772 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on midostaurin (the active ingredients of Rydapt) and Rydapt (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.