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Rythmol sr and Headache - a phase IV clinical study of FDA data

Summary:

Headache is reported as a side effect among people who take Rythmol sr (propafenone hydrochloride), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Xanax, and have Cardiac disorder.

The phase IV clinical study analyzes which people have Headache when taking Rythmol sr. It is created by eHealthMe based on reports of 516 people who have side effects when taking Rythmol sr from the FDA, and is updated regularly.

What is Rythmol sr?

Rythmol sr has active ingredients of propafenone hydrochloride. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 586 Rythmol sr users. Check the latest studies of Rythmol sr.

What is Headache?

Headache (pain in head) is found to be associated with 3,745 drugs and 5,767 conditions by eHealthMe. Check the latest studies of Headache.

On Apr, 25, 2026

516 people reported to have side effects when taking Rythmol sr.
Among them, 21 people (4.07%) have Headache.

Could Rythmol sr cause Headache?

Among these 21 people:

How long have people been on Rythmol sr when they have Headache? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 66.67 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 33.33 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Headache when taking Rythmol sr? *

  • female: 55 %
  • male: 45 %

What is the age of people who have Headache when taking Rythmol sr? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 14.29 %
  • 50-59: 0.0 %
  • 60+: 85.71 %

What are other drugs people take besides Rythmol sr? *

  1. Xanax: 4 people, 19.05%
  2. Coumadin: 3 people, 14.29%
  3. Cozaar: 3 people, 14.29%
  4. Premarin: 3 people, 14.29%
  5. Levothyroxine Sodium: 3 people, 14.29%
  6. Lopressor: 2 people, 9.52%
  7. Altace: 2 people, 9.52%
  8. Atenolol: 2 people, 9.52%
  9. Avapro: 2 people, 9.52%
  10. Celexa: 2 people, 9.52%

What are other side effects people have besides Headache? *

  1. Weakness: 7 people, 33.33%
  2. Dizziness: 7 people, 33.33%
  3. Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 4 people, 19.05%
  4. Fatigue (feeling of tiredness): 4 people, 19.05%
  5. High Blood Pressure: 3 people, 14.29%
  6. Numbness And Tingling (unusual prickling sensations): 3 people, 14.29%
  7. Gait Disturbance: 3 people, 14.29%
  8. Feeling Abnormal: 3 people, 14.29%
  9. Fall: 3 people, 14.29%
  10. Hypoaesthesia (reduced sense of touch or sensation): 3 people, 14.29%

What are the existing conditions these people have? *

  1. Insomnia (sleeplessness): 1 person, 4.76%
  2. Cardiac Disorder: 1 person, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Rythmol sr and have Headache?

- Check whether Headache is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Rythmol sr:

Headache treatments and more:

How severe was Headache and when was it recovered:

Expand to all the drugs that have ingredients of propafenone hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Rythmol sr:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Headache:

Browse all the conditions that are associated with Headache:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on propafenone hydrochloride (the active ingredients of Rythmol sr) and Rythmol sr (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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