Saizen and Coma - a phase IV clinical study of FDA data

Summary:

Coma is reported as a side effect among people who take Saizen (somatropin recombinant), especially for people who are female, 2-9 old, have been taking the drug for 1 - 6 months also take Levothyroxine Sodium, and have Growth hormone deficiency.

The phase IV clinical study analyzes which people have Coma when taking Saizen. It is created by eHealthMe based on reports of 3,115 people who have side effects when taking Saizen from the FDA, and is updated regularly.

What is Saizen?

Saizen has active ingredients of somatropin recombinant. eHealthMe is studying from 3,122 Saizen users. Check the latest studies of Saizen.

What is Coma?

Coma (state of unconsciousness lasting more than six hours) is found to be associated with 2,872 drugs and 3,175 conditions by eHealthMe. Check the latest studies of Coma.

On Nov, 27, 2025

3,115 people reported to have side effects when taking Saizen.
Among them, 9 people (0.29%) have Coma.

Among these 9 people:

How long have people been on Saizen when they have Coma? *

What is the gender of people who have Coma when taking Saizen? *

female: 66.67 %
male: 33.33 %

What is the age of people who have Coma when taking Saizen? *

What are other drugs people take besides Saizen? *

Levothyroxine Sodium: 3 people, 33.33%
Valproate Sodium: 2 people, 22.22%

What are other side effects people have besides Coma? *

Weight Decreased: 3 people, 33.33%
Nausea And Vomiting: 3 people, 33.33%
Depression: 2 people, 22.22%
Intracranial Pressure Increased (high pressure inside the skull and thus in the brain tissue and cerebrospinal fluid): 2 people, 22.22%
Cerebral Haemorrhage (bleeding within the brain): 2 people, 22.22%
Cardiac Disorder: 1 person, 11.11%
Fainting (loss of consciousness and postural tone): 1 person, 11.11%
Encephalopathy (functioning of the brain is affected by some agent or condition): 1 person, 11.11%
Drowsiness: 1 person, 11.11%
Difficulty In Walking: 1 person, 11.11%

What are the existing conditions these people have? *

Growth Hormone Deficiency: 3 people, 33.33%
Hypothalamo-Pituitary Disorders (loss of function in an endocrine gland due to failure of the pituitary gland to secrete hormones which stimulate that gland's function): 1 person, 11.11%
Body Height Below Normal: 1 person, 11.11%
Blood Growth Hormone Decreased: 1 person, 11.11%
Blood Growth Hormone Abnormal: 1 person, 11.11%

* Approximation only. Some reports may have incomplete information.

Do you take Saizen and have Coma?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Saizen:

Saizen (3,122 reports)

Coma treatments and more:

Coma (57,420 reports)

Browse all side effects of Saizen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Coma:

Coma (2,872 drugs)

Browse all the conditions that are associated with Coma:

Coma (3,175 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on somatropin recombinant (the active ingredients of Saizen) and Saizen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.