Saizen and Constipation - a phase IV clinical study of FDA data

Summary:

Constipation is reported as a side effect among people who take Saizen (somatropin recombinant), especially for people who are male, 2-9 old, have been taking the drug for 1 - 2 years also take Lorazepam, and have Growth hormone deficiency.

The phase IV clinical study analyzes which people have Constipation when taking Saizen. It is created by eHealthMe based on reports of 3,115 people who have side effects when taking Saizen from the FDA, and is updated regularly.

What is Saizen?

Saizen has active ingredients of somatropin recombinant. eHealthMe is studying from 3,122 Saizen users. Check the latest studies of Saizen.

What is Constipation?

Constipation is found to be associated with 3,005 drugs and 4,602 conditions by eHealthMe. Check the latest studies of Constipation.

On Apr, 28, 2026

3,115 people reported to have side effects when taking Saizen.
Among them, 24 people (0.77%) have Constipation.

Among these 24 people:

How long have people been on Saizen when they have Constipation? *

What is the gender of people who have Constipation when taking Saizen? *

female: 37.5 %
male: 62.5 %

What is the age of people who have Constipation when taking Saizen? *

What are other drugs people take besides Saizen? *

What are other side effects people have besides Constipation? *

Headache (pain in head): 7 people, 29.17%
Injection Site Pain: 5 people, 20.83%
Mean Cell Volume Increased (more than normal average red blood cell volume): 4 people, 16.67%
Thirst: 4 people, 16.67%
Stress And Anxiety: 4 people, 16.67%
Abdominal Pain: 3 people, 12.50%
Rickets (softening of bones): 3 people, 12.50%
Locked-In Syndrome (a condition in which a patient is aware and awake but cannot move or communicate verbally due to complete paralysis): 3 people, 12.50%
Dry Skin: 3 people, 12.50%
Brain Stem Glioma (cancerous glioma tumour in the brainstem): 3 people, 12.50%

What are the existing conditions these people have? *

Growth Hormone Deficiency: 14 people, 58.33%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 5 people, 20.83%
Wheezing (a high-pitched whistling sound made while you breath): 3 people, 12.50%
Body Height Below Normal: 3 people, 12.50%
Hypopituitarism (diminished hormone secretion by the pituitary gland, causing dwarfism in children and premature aging in adults): 2 people, 8.33%
Affective Disorder (mental disorder): 2 people, 8.33%
Blood Thyroid Stimulating Hormone Decreased: 2 people, 8.33%
Diabetes Insipidus (diabetes caused by a deficiency of the pituitary hormone vasopressin, which regulates kidney function): 2 people, 8.33%
Foetal Growth Restriction (poor growth of a baby while in the mother's womb during pregnancy): 2 people, 8.33%
Growth Retardation (delayed growth): 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Saizen and have Constipation?

- Check whether Constipation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Saizen:

Saizen (3,122 reports)

Constipation treatments and more:

Constipation (337,873 reports)

Browse all side effects of Saizen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Constipation:

Constipation (3,005 drugs)

Browse all the conditions that are associated with Constipation:

Constipation (4,602 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on somatropin recombinant (the active ingredients of Saizen) and Saizen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.