Samsca and Magnesium deficiency - a phase IV clinical study of FDA data

Summary:

Magnesium deficiency is reported only by a few people who take Samsca.

The study analyzes which people take Samsca and have Magnesium deficiency. It is created by eHealthMe based on reports of 8,134 people who have side effects while taking Samsca from the FDA, and is updated regularly.

What is Samsca?

Samsca has active ingredients of tolvaptan. eHealthMe is studying from 8,139 Samsca users. Check the latest studies of Samsca.

What is Magnesium deficiency?

Magnesium deficiency (lack of magnesium) is found to be associated with 78 drugs and 402 conditions by eHealthMe. Check the latest studies of Magnesium deficiency.

On May, 22, 2026

8,134 people reported to have side effects when taking Samsca.
Among them, 2 people (0.02%) have Magnesium deficiency.

Could Samsca cause Magnesium deficiency?

Among these 2 people:

How long have people been on Samsca when they have Magnesium deficiency? *

What is the gender of people who have Magnesium deficiency when taking Samsca? *

female: 100 %
male: 0.0 %

What is the age of people who have Magnesium deficiency when taking Samsca? *

What are other drugs people take besides Samsca? *

What are other side effects people have besides Magnesium deficiency? *

Wheezing (a high-pitched whistling sound made while you breath): 2 people, 100.00%
Muscle Spasms (muscle contraction): 2 people, 100.00%
C-Reactive Protein Increased: 2 people, 100.00%
Cardiac Failure: 2 people, 100.00%
Chest Pain: 2 people, 100.00%
Dyspnea (difficult or laboured breathing): 2 people, 100.00%
General Physical Health Deterioration (weak health status): 2 people, 100.00%
Haematemesis (vomiting of blood): 2 people, 100.00%
Oedema Peripheral (superficial swelling): 2 people, 100.00%
Oedema (fluid collection in tissue): 2 people, 100.00%

What are the existing conditions these people have? *

Renal Artery Stenosis (narrowing of renal artery): 2 people, 100.00%
Menopausal Symptoms: 2 people, 100.00%
Inappropriate Antidiuretic Hormone Secretion: 2 people, 100.00%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 2 people, 100.00%
Hyperparathyroidism (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium): 2 people, 100.00%
High Blood Pressure: 2 people, 100.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 100.00%
Gastritis (inflammation of stomach): 2 people, 100.00%
Dyspnea (difficult or laboured breathing): 2 people, 100.00%
Depression: 2 people, 100.00%

* Approximation only. Some reports may have incomplete information.

Do you take Samsca and have Magnesium deficiency?

- Check whether Magnesium deficiency is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Samsca:

Samsca (8,139 reports)

Browse all side effects of Samsca:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Magnesium deficiency:

Magnesium deficiency (78 drugs)

Browse all the conditions that are associated with Magnesium deficiency:

Magnesium deficiency (402 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on tolvaptan (the active ingredients of Samsca) and Samsca (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.