Sandimmune and Acute circulatory failure - a phase IV clinical study of FDA data

Summary:

Acute circulatory failure is reported as a side effect among people who take Sandimmune (cyclosporine), especially for people who are male, 60+ old, also take Prednisolone,.

The phase IV clinical study analyzes which people have Acute circulatory failure when taking Sandimmune. It is created by eHealthMe based on reports of 6,679 people who have side effects when taking Sandimmune from the FDA, and is updated regularly.

What is Sandimmune?

Sandimmune has active ingredients of cyclosporine. eHealthMe is studying from 6,694 Sandimmune users. Check the latest studies of Sandimmune.

What is Acute circulatory failure?

Acute circulatory failure (shock) is found to be associated with 378 drugs by eHealthMe. Check the latest studies of Acute circulatory failure.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

6,679 people reported to have side effects when taking Sandimmune.
Among them, 34 people (0.51%) have Acute circulatory failure.

Could Sandimmune cause Acute circulatory failure?

Among these 34 people:

What is the gender of people who have Acute circulatory failure when taking Sandimmune? *

female: 26.47 %
male: 73.53 %

What is the age of people who have Acute circulatory failure when taking Sandimmune? *

What are other drugs people take besides Sandimmune? *

What are other side effects people have besides Acute circulatory failure? *

Fever: 9 people, 26.47%
Multi-Organ Failure (multisystem organ failure): 6 people, 17.65%
Malaise (a feeling of general discomfort or uneasiness): 6 people, 17.65%
Mydriasis (a dilation of the pupil): 5 people, 14.71%
C-Reactive Protein Increased: 5 people, 14.71%
Liver Function Tests Nos Abnormal: 5 people, 14.71%
Chills (felling of cold): 5 people, 14.71%
Iiird Nerve Paralysis (totally closed eyelid and a down and out deviation of the eye): 5 people, 14.71%
Diplopia (double vision): 5 people, 14.71%
Pupillary Reflex Impaired: 5 people, 14.71%

* Approximation only. Some reports may have incomplete information.

Do you take Sandimmune and have Acute circulatory failure?

- Check whether Acute circulatory failure is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sandimmune:

Sandimmune (6,694 reports)

Browse all side effects of Sandimmune:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Acute circulatory failure:

Acute circulatory failure (378 drugs)

Browse all the conditions that are associated with Acute circulatory failure:

Acute circulatory failure

Related publications that referenced our studies

O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .
O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .

How the study uses the data?

The study uses data from the FDA. It is based on cyclosporine (the active ingredients of Sandimmune) and Sandimmune (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.