Sandimmune and Haptoglobin decreased - a phase IV clinical study of FDA data

Summary:

Haptoglobin decreased is reported as a side effect among people who take Sandimmune (cyclosporine), especially for people who are female, 2-9 old, have been taking the drug for < 1 month also take Cyclophosphamide, and have Graft versus host disease.

The phase IV clinical study analyzes which people have Haptoglobin decreased when taking Sandimmune. It is created by eHealthMe based on reports of 6,679 people who have side effects when taking Sandimmune from the FDA, and is updated regularly.

What is Sandimmune?

Sandimmune has active ingredients of cyclosporine. eHealthMe is studying from 6,694 Sandimmune users. Check the latest studies of Sandimmune.

What is Haptoglobin decreased?

Haptoglobin decreased is found to be associated with 131 drugs and 277 conditions by eHealthMe. Check the latest studies of Haptoglobin decreased.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 17, 2026

6,679 people reported to have side effects when taking Sandimmune.
Among them, 12 people (0.18%) have Haptoglobin decreased.

Could Sandimmune cause Haptoglobin decreased?

Among these 12 people:

How long have people been on Sandimmune when they have Haptoglobin decreased? *

What is the gender of people who have Haptoglobin decreased when taking Sandimmune? *

female: 58.33 %
male: 41.67 %

What is the age of people who have Haptoglobin decreased when taking Sandimmune? *

What are other drugs people take besides Sandimmune? *

What are other side effects people have besides Haptoglobin decreased? *

Blood Lactate Dehydrogenase Increased: 6 people, 50.00%
Haemolytic Anaemia (anaemia due to haemolysis): 5 people, 41.67%
Blood Bilirubin Increased: 5 people, 41.67%
Thrombotic Microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury): 4 people, 33.33%
Thrombocytopenia (decrease of platelets in blood): 4 people, 33.33%
Fever: 3 people, 25.00%
Focal Glomerulosclerosis (disease that attacks the kidney's filtering system (glomeruli) causing serious scarring): 2 people, 16.67%
Mitral Valve Incompetence (inefficient heart valve): 2 people, 16.67%
Multi-Organ Failure (multisystem organ failure): 2 people, 16.67%
Oxygen Saturation Decreased: 2 people, 16.67%

What are the existing conditions these people have? *

Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Sandimmune and have Haptoglobin decreased?

- Check whether Haptoglobin decreased is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sandimmune:

Sandimmune (6,694 reports)

Browse all side effects of Sandimmune:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Haptoglobin decreased:

Haptoglobin decreased (131 drugs)

Browse all the conditions that are associated with Haptoglobin decreased:

Haptoglobin decreased (277 conditions)

Related publications that referenced our studies

O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .
O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .

How the study uses the data?

The study uses data from the FDA. It is based on cyclosporine (the active ingredients of Sandimmune) and Sandimmune (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.