Sandimmune and Heart attack - a phase IV clinical study of FDA data

Summary:

Heart attack is reported as a side effect among people who take Sandimmune (cyclosporine), especially for people who are male, 50-59 old, have been taking the drug for 2 - 5 years also take Prednisone, and have High blood cholesterol.

The phase IV clinical study analyzes which people have Heart attack when taking Sandimmune. It is created by eHealthMe based on reports of 6,679 people who have side effects when taking Sandimmune from the FDA, and is updated regularly.

What is Sandimmune?

Sandimmune has active ingredients of cyclosporine. eHealthMe is studying from 6,694 Sandimmune users. Check the latest studies of Sandimmune.

What is Heart attack?

Heart attack is found to be associated with 2,482 drugs and 3,296 conditions by eHealthMe. Check the latest studies of Heart attack.

On Jul, 18, 2026

6,679 people reported to have side effects when taking Sandimmune.
Among them, 47 people (0.7%) have Heart attack.

Among these 47 people:

How long have people been on Sandimmune when they have Heart attack? *

What is the gender of people who have Heart attack when taking Sandimmune? *

female: 25.53 %
male: 74.47 %

What is the age of people who have Heart attack when taking Sandimmune? *

What are other drugs people take besides Sandimmune? *

What are other side effects people have besides Heart attack? *

Coronary Heart Disease (narrowing or blockage of the coronary arteries): 8 people, 17.02%
Sepsis (a severe blood infection that can lead to organ failure and death): 6 people, 12.77%
Pneumonia: 6 people, 12.77%
Acute Kidney Failure: 6 people, 12.77%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 5 people, 10.64%
Fever: 5 people, 10.64%
Kidney Transplant Rejection: 4 people, 8.51%
Atherosclerosis (disorder of the arteries): 4 people, 8.51%
Cytomegalovirus Infection: 4 people, 8.51%
Multi-Organ Failure (multisystem organ failure): 4 people, 8.51%

What are the existing conditions these people have? *

High Blood Pressure: 3 people, 6.38%
High Blood Cholesterol: 3 people, 6.38%
Immunodeficiency Disorders: 2 people, 4.26%
Feeding Disorder (when children refuse to eat certain food groups): 2 people, 4.26%
Urination - Excessive Volume: 1 person, 2.13%
Pyoderma Gangrenosum (ulcerating condition of skin that results in heaped borders with a typical appearance): 1 person, 2.13%
Polymyositis (inflammatory muscle disease that causes weakness of the skeletal muscles): 1 person, 2.13%
Pain: 1 person, 2.13%
Osteoporosis (bones weak and more likely to break): 1 person, 2.13%
Nephrotic Syndrome (kidney disease with proteinuria, hypoalbuminemia, and oedema): 1 person, 2.13%

* Approximation only. Some reports may have incomplete information.

Do you take Sandimmune and have Heart attack?

- Check whether Heart attack is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sandimmune:

Sandimmune (6,694 reports)

Heart attack treatments and more:

Heart attack (266,145 reports)

Browse all side effects of Sandimmune:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Heart attack:

Heart attack (2,482 drugs)

Browse all the conditions that are associated with Heart attack:

Heart attack (3,296 conditions)

Related publications that referenced our studies

O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .
O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .

How the study uses the data?

The study uses data from the FDA. It is based on cyclosporine (the active ingredients of Sandimmune) and Sandimmune (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.