Saphris and Hypoglycaemia aggravated - a phase IV clinical study of FDA data

Summary:

Hypoglycaemia aggravated is reported as a side effect among people who take Saphris (asenapine maleate), especially for people who are male, 50-59 old, have been taking the drug for < 1 month also take Lamotrigine, and have Affective disorder.

The phase IV clinical study analyzes which people have Hypoglycaemia aggravated when taking Saphris. It is created by eHealthMe based on reports of 8,449 people who have side effects when taking Saphris from the FDA, and is updated regularly.

What is Saphris?

Saphris has active ingredients of asenapine maleate. It is often used in bipolar i disorder. eHealthMe is studying from 8,688 Saphris users. Check the latest studies of Saphris.

What is Hypoglycaemia aggravated?

Hypoglycaemia aggravated (deficiency of glucose in the bloodstream) is found to be associated with 1,481 drugs and 536 conditions by eHealthMe. Check the latest studies of Hypoglycaemia aggravated.

On Jul, 02, 2026

8,449 people reported to have side effects when taking Saphris.
Among them, 24 people (0.28%) have Hypoglycaemia aggravated.

Could Saphris cause Hypoglycaemia aggravated?

Among these 24 people:

How long have people been on Saphris when they have Hypoglycaemia aggravated? *

What is the gender of people who have Hypoglycaemia aggravated when taking Saphris? *

female: 30 %
male: 70 %

What is the age of people who have Hypoglycaemia aggravated when taking Saphris? *

What are other drugs people take besides Saphris? *

What are other side effects people have besides Hypoglycaemia aggravated? *

Depression: 19 people, 79.17%
Hallucination, Auditory (perceiving sounds without auditory stimulus): 16 people, 66.67%
Psychotic Disorder: 16 people, 66.67%
Diabetes: 16 people, 66.67%
Hallucination, Visual (seeing things that aren't there): 16 people, 66.67%
Suicidal Ideation: 16 people, 66.67%
Stress And Anxiety: 16 people, 66.67%
Weight Increased: 4 people, 16.67%
Schizoaffective Disorder (a mental disorder characterized by disordered thought): 3 people, 12.50%
Appetite Disorder (abnormal eating habits): 3 people, 12.50%

What are the existing conditions these people have? *

Depression: 19 people, 79.17%
Affective Disorder (mental disorder): 19 people, 79.17%
Stress And Anxiety: 16 people, 66.67%
Sleep Disorder: 16 people, 66.67%
Insomnia (sleeplessness): 16 people, 66.67%
Heart Attack: 14 people, 58.33%
Diabetes: 13 people, 54.17%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 11 people, 45.83%
Chest Pain: 11 people, 45.83%
Reflux Gastritis (a condition in which the lining of a person's stomach becomes inflamed as a result of exposure to bile): 5 people, 20.83%

* Approximation only. Some reports may have incomplete information.

Do you take Saphris and have Hypoglycaemia aggravated?

- Check whether Hypoglycaemia aggravated is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Saphris:

Saphris (8,688 reports)

Browse all side effects of Saphris:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypoglycaemia aggravated:

Hypoglycaemia aggravated (1,481 drugs)

Browse all the conditions that are associated with Hypoglycaemia aggravated:

Hypoglycaemia aggravated (536 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on asenapine maleate (the active ingredients of Saphris) and Saphris (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.