Savella and Broken bone - a phase IV clinical study of FDA data

Summary:

Broken bone is reported as a side effect among people who take Savella (milnacipran hydrochloride), especially for people who are female, 50-59 old, have been taking the drug for 2 - 5 years also take Lyrica, and have Gastroesophageal reflux disease.

The phase IV clinical study analyzes which people have Broken bone when taking Savella. It is created by eHealthMe based on reports of 6,561 people who have side effects when taking Savella from the FDA, and is updated regularly.

What is Savella?

Savella has active ingredients of milnacipran hydrochloride. It is often used in fibromyalgia. eHealthMe is studying from 7,529 Savella users. Check the latest studies of Savella.

What is Broken bone?

Broken bone is found to be associated with 1,306 drugs and 1,493 conditions by eHealthMe. Check the latest studies of Broken bone.

On Jul, 13, 2026

6,561 people reported to have side effects when taking Savella.
Among them, 11 people (0.17%) have Broken bone.

Among these 11 people:

How long have people been on Savella when they have Broken bone? *

What is the gender of people who have Broken bone when taking Savella? *

female: 90.91 %
male: 9.09 %

What is the age of people who have Broken bone when taking Savella? *

What are other drugs people take besides Savella? *

What are other side effects people have besides Broken bone? *

Fall: 5 people, 45.45%
Rib Fracture: 4 people, 36.36%
Bone Disorder: 4 people, 36.36%
Pain In Extremity: 4 people, 36.36%
Osteoporosis (bones weak and more likely to break): 4 people, 36.36%
Weakness: 4 people, 36.36%
Carpal Tunnel Syndrome (nerve compression at wrist results numbness weakness, pain , swelling): 4 people, 36.36%
Malaise (a feeling of general discomfort or uneasiness): 4 people, 36.36%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 27.27%
Neuropathy Peripheral (surface nerve damage): 3 people, 27.27%

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 36.36%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 27.27%
Weight Decreased: 2 people, 18.18%
Nausea (feeling of having an urge to vomit): 2 people, 18.18%
Breakthrough Pain: 2 people, 18.18%
High Blood Pressure: 2 people, 18.18%
Hyperhidrosis (abnormally increased sweating): 2 people, 18.18%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 18.18%
Thyroid Diseases: 2 people, 18.18%
Insomnia (sleeplessness): 2 people, 18.18%

* Approximation only. Some reports may have incomplete information.

Do you take Savella and have Broken bone?

- Check whether Broken bone is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Savella:

Savella (7,529 reports)

Broken bone treatments and more:

Broken bone (35,552 reports)

Browse all side effects of Savella:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Broken bone:

Broken bone (1,306 drugs)

Browse all the conditions that are associated with Broken bone:

Broken bone (1,493 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on milnacipran hydrochloride (the active ingredients of Savella) and Savella (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.