Savella and Inflammation - a phase IV clinical study of FDA data

Summary:

Inflammation is reported as a side effect among people who take Savella (milnacipran hydrochloride), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Folic Acid, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Inflammation when taking Savella. It is created by eHealthMe based on reports of 6,561 people who have side effects when taking Savella from the FDA, and is updated regularly.

What is Savella?

Savella has active ingredients of milnacipran hydrochloride. It is often used in fibromyalgia. eHealthMe is studying from 7,529 Savella users. Check the latest studies of Savella.

What is Inflammation?

Inflammation is found to be associated with 1,712 drugs and 1,878 conditions by eHealthMe. Check the latest studies of Inflammation.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

6,561 people reported to have side effects when taking Savella.
Among them, 30 people (0.46%) have Inflammation.

Among these 30 people:

How long have people been on Savella when they have Inflammation? *

What is the gender of people who have Inflammation when taking Savella? *

female: 93.1 %
male: 6.9 %

What is the age of people who have Inflammation when taking Savella? *

What are other drugs people take besides Savella? *

What are other side effects people have besides Inflammation? *

Nausea (feeling of having an urge to vomit): 10 people, 33.33%
Joint Pain: 9 people, 30.00%
Chest Pain: 5 people, 16.67%
Insomnia (sleeplessness): 5 people, 16.67%
Fall: 5 people, 16.67%
Drug Ineffective: 5 people, 16.67%
Dehydration (dryness resulting from the removal of water): 5 people, 16.67%
Constipation: 5 people, 16.67%
Stress And Anxiety: 5 people, 16.67%
Malaise (a feeling of general discomfort or uneasiness): 5 people, 16.67%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 14 people, 46.67%
Stress And Anxiety: 7 people, 23.33%
Constipation: 6 people, 20.00%
Nausea (feeling of having an urge to vomit): 6 people, 20.00%
Muscle Spasms (muscle contraction): 6 people, 20.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 16.67%
Panic Disorder: 5 people, 16.67%
Restless Leg Syndrome (a powerful urge to move your legs): 4 people, 13.33%
Dementia (madness): 3 people, 10.00%
Bowel Movement Irregularity: 3 people, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Savella and have Inflammation?

- Check whether Inflammation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Savella:

Savella (7,529 reports)

Inflammation treatments and more:

Inflammation (78,911 reports)

Browse all side effects of Savella:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Inflammation:

Inflammation (1,712 drugs)

Browse all the conditions that are associated with Inflammation:

Inflammation (1,878 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on milnacipran hydrochloride (the active ingredients of Savella) and Savella (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.