Savella and Otitis - a phase IV clinical study of FDA data

Summary:

Otitis is reported as a side effect among people who take Savella (milnacipran hydrochloride), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Vitamin D3, and have Immunodeficiency common variable.

The phase IV clinical study analyzes which people have Otitis when taking Savella. It is created by eHealthMe based on reports of 6,561 people who have side effects when taking Savella from the FDA, and is updated regularly.

What is Savella?

Savella has active ingredients of milnacipran hydrochloride. It is often used in fibromyalgia. eHealthMe is studying from 7,529 Savella users. Check the latest studies of Savella.

What is Otitis?

Otitis (ear infection) is found to be associated with 1,429 drugs and 1,828 conditions by eHealthMe. Check the latest studies of Otitis.

On Jul, 05, 2026

6,561 people reported to have side effects when taking Savella.
Among them, 23 people (0.35%) have Otitis.

Among these 23 people:

How long have people been on Savella when they have Otitis? *

What is the gender of people who have Otitis when taking Savella? *

female: 100 %
male: 0.0 %

What is the age of people who have Otitis when taking Savella? *

What are other drugs people take besides Savella? *

What are other side effects people have besides Otitis? *

Sinusitis (inflammation of sinus): 10 people, 43.48%
Infection: 8 people, 34.78%
Urinary Tract Infection: 8 people, 34.78%
Migraine (headache): 7 people, 30.43%
Headache (pain in head): 6 people, 26.09%
Tenderness (pain or discomfort when an affected area is touched): 5 people, 21.74%
Dry Eyes (lack of adequate tears): 5 people, 21.74%
Renal Abscess (pus in kidney): 5 people, 21.74%
Panic Disorder: 5 people, 21.74%
Fatigue (feeling of tiredness): 5 people, 21.74%

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 6 people, 26.09%
Primary Immunodeficiency Syndrome: 5 people, 21.74%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 13.04%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 13.04%
Hereditary Angioedema (recurrent episodes of severe swelling): 3 people, 13.04%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 8.70%
Athlete's Foot (a fungal infection affecting the skin between the toes): 2 people, 8.70%
Acarodermatitis (skin inflammation caused by mites (acarids)): 2 people, 8.70%
Stress And Anxiety: 1 person, 4.35%
Migraine (headache): 1 person, 4.35%

* Approximation only. Some reports may have incomplete information.

Do you take Savella and have Otitis?

- Check whether Otitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Savella:

Savella (7,529 reports)

Otitis treatments and more:

Otitis (36,446 reports)

Browse all side effects of Savella:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Otitis:

Otitis (1,429 drugs)

Browse all the conditions that are associated with Otitis:

Otitis (1,828 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on milnacipran hydrochloride (the active ingredients of Savella) and Savella (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.