Savella and Thrombocytopenia - a phase IV clinical study of FDA data

Summary:

Thrombocytopenia is reported as a side effect among people who take Savella (milnacipran hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Revlimid, and have Nausea.

The phase IV clinical study analyzes which people have Thrombocytopenia when taking Savella. It is created by eHealthMe based on reports of 6,561 people who have side effects when taking Savella from the FDA, and is updated regularly.

What is Savella?

Savella has active ingredients of milnacipran hydrochloride. It is often used in fibromyalgia. eHealthMe is studying from 7,529 Savella users. Check the latest studies of Savella.

What is Thrombocytopenia?

Thrombocytopenia (decrease of platelets in blood) is found to be associated with 2,791 drugs and 4,870 conditions by eHealthMe. Check the latest studies of Thrombocytopenia.

On Jul, 17, 2026

6,561 people reported to have side effects when taking Savella.
Among them, 16 people (0.24%) have Thrombocytopenia.

Among these 16 people:

How long have people been on Savella when they have Thrombocytopenia? *

What is the gender of people who have Thrombocytopenia when taking Savella? *

female: 93.75 %
male: 6.25 %

What is the age of people who have Thrombocytopenia when taking Savella? *

What are other drugs people take besides Savella? *

What are other side effects people have besides Thrombocytopenia? *

Chest Pain: 6 people, 37.50%
Hypotension (abnormally low blood pressure): 4 people, 25.00%
Respiratory Distress (difficulty in breathing): 4 people, 25.00%
Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 4 people, 25.00%
Blood Creatinine Increased: 4 people, 25.00%
Acidosis (build-up of carbon dioxide in the blood): 4 people, 25.00%
High Blood Pressure: 3 people, 18.75%
Peripheral Swelling: 3 people, 18.75%
Fluid Overload (too much fluid in the blood): 3 people, 18.75%
Rashes (redness): 3 people, 18.75%

What are the existing conditions these people have? *

Nausea (feeling of having an urge to vomit): 7 people, 43.75%
Multiple Myeloma (cancer of the plasma cells): 5 people, 31.25%
Stress And Anxiety: 4 people, 25.00%
Nausea And Vomiting: 4 people, 25.00%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 4 people, 25.00%
Herpes Zoster: 4 people, 25.00%
Blood Calcium Increased: 4 people, 25.00%
Restless Leg Syndrome (a powerful urge to move your legs): 4 people, 25.00%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 12.50%
Ovarian Cancer (cancer of ovary): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Savella and have Thrombocytopenia?

- Check whether Thrombocytopenia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Savella:

Savella (7,529 reports)

Thrombocytopenia treatments and more:

Thrombocytopenia (285,083 reports)

Browse all side effects of Savella:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Thrombocytopenia:

Thrombocytopenia (2,791 drugs)

Browse all the conditions that are associated with Thrombocytopenia:

Thrombocytopenia (4,870 conditions)

Related publications that referenced our studies

YavasogluI, I., TurgutkayaII, A., & BolamanIII, Z., "Chlorella-induced thrombocytopenia", DATA, 2018 Jan .
Rasmy A, Rahal M, Kisana M, Ahmad S, Salah A, "Morphine induced thrombocytopenia: A case report", Journal of Case Reports and Images in Oncology, 2015 Dec .
Onder H, Arsava EM, Arat A, Topcuoglu MA, "Acute middle cerebral artery occlusion treated by thrombectomy in a patient with myelodysplastic syndrome and severe thrombocytopenia", Journal of vascular and interventional neurology, 2015 Jan .
YavasogluI, I., TurgutkayaII, A., & BolamanIII, Z., "Chlorella-induced thrombocytopenia", DATA, 2018 Jan .
Rasmy A, Rahal M, Kisana M, Ahmad S, Salah A, "Morphine induced thrombocytopenia: A case report", Journal of Case Reports and Images in Oncology, 2015 Dec .
Onder H, Arsava EM, Arat A, Topcuoglu MA, "Acute middle cerebral artery occlusion treated by thrombectomy in a patient with myelodysplastic syndrome and severe thrombocytopenia", Journal of vascular and interventional neurology, 2015 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on milnacipran hydrochloride (the active ingredients of Savella) and Savella (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.