Saxenda and Hypothyroidism - a phase IV clinical study of FDA data

Summary:

Hypothyroidism is reported as a side effect among people who take Saxenda (liraglutide recombinant), especially for people who are female, 40-49 old, have been taking the drug for 1 - 6 months also take Pantoprazole, and have Asthma.

The phase IV clinical study analyzes which people have Hypothyroidism when taking Saxenda. It is created by eHealthMe based on reports of 6,333 people who have side effects when taking Saxenda from the FDA, and is updated regularly.

What is Saxenda?

Saxenda has active ingredients of liraglutide recombinant. It is often used in weight loss. eHealthMe is studying from 6,735 Saxenda users. Check the latest studies of Saxenda.

What is Hypothyroidism?

Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development) is found to be associated with 1,617 drugs and 2,600 conditions by eHealthMe. Check the latest studies of Hypothyroidism.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 23, 2026

6,333 people reported to have side effects when taking Saxenda.
Among them, 13 people (0.21%) have Hypothyroidism.

Could Saxenda cause Hypothyroidism?

Among these 13 people:

How long have people been on Saxenda when they have Hypothyroidism? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 100 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Hypothyroidism when taking Saxenda? *

  • female: 91.67 %
  • male: 8.33 %

What is the age of people who have Hypothyroidism when taking Saxenda? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 75 %
  • 50-59: 25 %
  • 60+: 0.0 %

What are other drugs people take besides Saxenda? *

  1. Zoloft: 4 people, 30.77%
  2. Symbicort: 4 people, 30.77%
  3. Spiriva Respimat: 4 people, 30.77%
  4. Singulair: 4 people, 30.77%
  5. Metformin: 4 people, 30.77%
  6. Pantoprazole: 4 people, 30.77%
  7. Nucala: 3 people, 23.08%
  8. Atrovent: 3 people, 23.08%
  9. Albuterol Sulfate: 2 people, 15.38%
  10. Prednisone: 2 people, 15.38%

What are other side effects people have besides Hypothyroidism? *

  1. Wheezing (a high-pitched whistling sound made while you breath): 4 people, 30.77%
  2. Obstructive Airways Disorder (a progressive disease that makes it hard to breathe): 4 people, 30.77%
  3. Dyspnea (difficult or laboured breathing): 4 people, 30.77%
  4. Asthma: 4 people, 30.77%
  5. Stress And Anxiety: 4 people, 30.77%
  6. Sleep Disorder: 3 people, 23.08%
  7. Weight Increased: 2 people, 15.38%
  8. Full Blood Count Abnormal: 2 people, 15.38%
  9. Blood Count Abnormal: 2 people, 15.38%
  10. Pancreatitis (inflammation of pancreas): 1 person, 7.69%

What are the existing conditions these people have? *

  1. Asthma: 3 people, 23.08%
  2. Weight Increased: 1 person, 7.69%
  3. Seasonal Allergy (allergic condition due to certain season): 1 person, 7.69%
  4. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 7.69%
  5. Constipation: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Saxenda and have Hypothyroidism?

- Check whether Hypothyroidism is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Saxenda:

Hypothyroidism treatments and more:

How severe was Hypothyroidism and when was it recovered:

Expand to all the drugs that have ingredients of liraglutide recombinant:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Saxenda:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypothyroidism:

Browse all the conditions that are associated with Hypothyroidism:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on liraglutide recombinant (the active ingredients of Saxenda) and Saxenda (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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