Senna alexandrina and Heart attack - a phase IV clinical study of FDA data

Summary:

Heart attack is reported as a side effect among people who take Senna alexandrina (senna), especially for people who are female, 60+ old, also take Metformin, and have Constipation.

The phase IV clinical study analyzes which people have Heart attack when taking Senna alexandrina. It is created by eHealthMe based on reports of 2,852 people who have side effects when taking Senna alexandrina from the FDA, and is updated regularly.

What is Senna alexandrina?

Senna alexandrina has active ingredients of senna. eHealthMe is studying from 2,853 Senna alexandrina users. Check the latest studies of Senna alexandrina.

What is Heart attack?

Heart attack is found to be associated with 2,475 drugs and 3,298 conditions by eHealthMe. Check the latest studies of Heart attack.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

2,852 people reported to have side effects when taking Senna alexandrina.
Among them, 13 people (0.46%) have Heart attack.

Could Senna alexandrina cause Heart attack?

Among these 13 people:

What is the gender of people who have Heart attack when taking Senna alexandrina? *

female: 53.85 %
male: 46.15 %

What is the age of people who have Heart attack when taking Senna alexandrina? *

What are other drugs people take besides Senna alexandrina? *

Aspirin: 3 people, 23.08%
Metformin: 3 people, 23.08%
Lasix: 2 people, 15.38%
Imbruvica: 2 people, 15.38%
Humira: 2 people, 15.38%
Zopiclone: 1 person, 7.69%
Dobutamine Hydrochloride: 1 person, 7.69%
Levophed: 1 person, 7.69%
Lescol: 1 person, 7.69%
Lansoprazole: 1 person, 7.69%

What are other side effects people have besides Heart attack? *

Arrhythmias (irregular heartbeat): 2 people, 15.38%
Cardiac Arrest: 2 people, 15.38%
Joint Swelling: 2 people, 15.38%
White Blood Cell Count Increased: 1 person, 7.69%
Depression: 1 person, 7.69%
Hepatic Cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue): 1 person, 7.69%
Helicobacter Infection (helicobacter pylori (h. pylori) infects stomach): 1 person, 7.69%
Gastrointestinal Motility Disorder (abnormal intestinal contractions): 1 person, 7.69%
Gastritis (inflammation of stomach): 1 person, 7.69%
Fear: 1 person, 7.69%

What are the existing conditions these people have? *

High Blood Pressure: 3 people, 23.08%
Constipation: 3 people, 23.08%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 1 person, 7.69%
Cellulitis (infection under the skin): 1 person, 7.69%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 1 person, 7.69%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 7.69%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 1 person, 7.69%
Depression: 1 person, 7.69%
Essential Hypertension (primary hypertension): 1 person, 7.69%
Gastric Ulcer (stomach ulcer): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Senna alexandrina and have Heart attack?

- Check whether Heart attack is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Senna alexandrina:

Senna alexandrina (2,853 reports)

Heart attack treatments and more:

Heart attack (266,145 reports)

Browse all side effects of Senna alexandrina:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Heart attack:

Heart attack (2,475 drugs)

Browse all the conditions that are associated with Heart attack:

Heart attack (3,298 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on senna (the active ingredients of Senna alexandrina) and Senna alexandrina (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.