Senna and Enuresis aggravated - a phase IV clinical study of FDA data
Summary:
Enuresis aggravated is reported as a side effect among people who take Senna (senna), especially for people who are male, 10-19 old, have been taking the drug for 1 - 2 years also take Clozaril, and have Schizophrenia.
The phase IV clinical study analyzes which people have Enuresis aggravated when taking Senna. It is created by eHealthMe based on reports of 37,042 people who have side effects when taking Senna from the FDA, and is updated regularly.
What is Senna?
Senna has active ingredients of senna. It is often used in constipation. eHealthMe is studying from 37,302 Senna users. Check the latest studies of Senna.
What is Enuresis aggravated?
Enuresis aggravated (repeated inability to control urination) is found to be associated with 538 drugs and 196 conditions by eHealthMe. Check the latest studies of Enuresis aggravated.
37,042 people reported to have side effects when taking Senna.
Among them, 22 people (0.06%) have Enuresis aggravated.

Among these 22 people:
How long have people been on Senna when they have Enuresis aggravated? *
- < 1 month: 0.0 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 100 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Enuresis aggravated when taking Senna? *
- female: 35 %
- male: 65 %
What is the age of people who have Enuresis aggravated when taking Senna? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 81.82 %
- 20-29: 0.0 %
- 30-39: 0.0 %
- 40-49: 0.0 %
- 50-59: 9.09 %
- 60+: 9.09 %
What are other drugs people take besides Senna? *
- Clozaril: 7 people, 31.82%
- Effexor: 6 people, 27.27%
- Xyrem: 6 people, 27.27%
- Olanzapine: 5 people, 22.73%
- Vitamin D3: 5 people, 22.73%
- Vitamin B12: 4 people, 18.18%
- Miralax: 4 people, 18.18%
- Clozapine: 3 people, 13.64%
- Vyvanse: 3 people, 13.64%
- Metronidazole: 3 people, 13.64%
What are other side effects people have besides Enuresis aggravated? *
- Dehydration (dryness resulting from the removal of water): 13 people, 59.09%
- Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 10 people, 45.45%
- Salivary Hypersecretion (excess saliva secretion): 10 people, 45.45%
- Nausea (feeling of having an urge to vomit): 10 people, 45.45%
- Pneumonia: 10 people, 45.45%
- Gastroenteritis (inflammation of stomach and intestine): 9 people, 40.91%
- Diarrhea: 8 people, 36.36%
- Nausea And Vomiting: 7 people, 31.82%
- Suicidal Ideation: 6 people, 27.27%
- Weight Decreased: 6 people, 27.27%
What are the existing conditions these people have? *
- Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 10 people, 45.45%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 8 people, 36.36%
- Salivary Hypersecretion (excess saliva secretion): 6 people, 27.27%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 6 people, 27.27%
- Weight Loss: 4 people, 18.18%
- Weight Decreased: 4 people, 18.18%
- Drowsiness: 4 people, 18.18%
- Affective Disorder (mental disorder): 2 people, 9.09%
- Acne (skin problems that cause pimples): 2 people, 9.09%
- Wheezing (a high-pitched whistling sound made while you breath): 1 person, 4.55%
* Approximation only. Some reports may have incomplete information.
Do you take Senna and have Enuresis aggravated?
- Check whether Enuresis aggravated is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Senna:
- Senna (37,302 reports)
Enuresis aggravated treatments and more:
- Enuresis aggravated (6 reports)
How severe was Enuresis aggravated and when was it recovered:
Expand to all the drugs that have ingredients of senna:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Senna:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Enuresis aggravated:
- Enuresis aggravated (538 drugs)
Browse all the conditions that are associated with Enuresis aggravated:
- Enuresis aggravated (196 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on senna (the active ingredients of Senna) and Senna (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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