Senna and Flank pain - a phase IV clinical study of FDA data

Summary:

Flank pain is reported as a side effect among people who take Senna (senna), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Tylenol, and have Pain.

The phase IV clinical study analyzes which people have Flank pain when taking Senna. It is created by eHealthMe based on reports of 37,042 people who have side effects when taking Senna from the FDA, and is updated regularly.

What is Senna?

Senna has active ingredients of senna. It is often used in constipation. eHealthMe is studying from 37,302 Senna users. Check the latest studies of Senna.

What is Flank pain?

Flank pain (a distressing sensation experienced around the lower back and the upper abdomen) is found to be associated with 1,133 drugs and 1,476 conditions by eHealthMe. Check the latest studies of Flank pain.



On Jul, 03, 2026

37,042 people reported to have side effects when taking Senna.
Among them, 83 people (0.22%) have Flank pain.

Could Senna cause Flank pain?

Among these 83 people:

How long have people been on Senna when they have Flank pain? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Flank pain when taking Senna? *

  • female: 62.65 %
  • male: 37.35 %

What is the age of people who have Flank pain when taking Senna? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 1.28 %
  • 20-29: 6.41 %
  • 30-39: 7.69 %
  • 40-49: 3.85 %
  • 50-59: 17.95 %
  • 60+: 62.82 %

What are other drugs people take besides Senna? *

  1. Tylenol: 32 people, 38.55%
  2. Miralax: 25 people, 30.12%
  3. Ondansetron: 22 people, 26.51%
  4. Furosemide: 18 people, 21.69%
  5. Zofran: 18 people, 21.69%
  6. Dilaudid: 18 people, 21.69%
  7. Sodium Chloride: 18 people, 21.69%
  8. Ativan: 18 people, 21.69%
  9. Colace: 17 people, 20.48%
  10. Protonix: 17 people, 20.48%

What are other side effects people have besides Flank pain? *

  1. Chest Pain: 32 people, 38.55%
  2. Dyspnea (difficult or laboured breathing): 27 people, 32.53%
  3. Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 25 people, 30.12%
  4. Nausea (feeling of having an urge to vomit): 24 people, 28.92%
  5. Back Pain: 24 people, 28.92%
  6. Urinary Tract Infection: 21 people, 25.30%
  7. Nausea And Vomiting: 21 people, 25.30%
  8. Pleural Effusion (water on the lungs): 21 people, 25.30%
  9. Pain In Extremity: 20 people, 24.10%
  10. Abdominal Pain: 18 people, 21.69%

What are the existing conditions these people have? *

  1. Pain: 26 people, 31.33%
  2. Nausea (feeling of having an urge to vomit): 18 people, 21.69%
  3. Stress And Anxiety: 18 people, 21.69%
  4. High Blood Pressure: 14 people, 16.87%
  5. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 13 people, 15.66%
  6. Dizziness: 11 people, 13.25%
  7. Seasonal Allergy (allergic condition due to certain season): 11 people, 13.25%
  8. Type 2 Diabetes: 10 people, 12.05%
  9. Sinusitis (inflammation of sinus): 10 people, 12.05%
  10. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 9 people, 10.84%

* Approximation only. Some reports may have incomplete information.

Do you take Senna and have Flank pain?

- Check whether Flank pain is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Senna:

Flank pain treatments and more:

How severe was Flank pain and when was it recovered:

Expand to all the drugs that have ingredients of senna:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Senna:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Flank pain:

Browse all the conditions that are associated with Flank pain:


How the study uses the data?

The study uses data from the FDA. It is based on senna (the active ingredients of Senna) and Senna (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: