Senna and Lymphopenia - a phase IV clinical study of FDA data

Summary:

Lymphopenia is reported as a side effect among people who take Senna (senna), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Compazine, and have Acute lymphocytic leukemia (all).

The phase IV clinical study analyzes which people have Lymphopenia when taking Senna. It is created by eHealthMe based on reports of 37,042 people who have side effects when taking Senna from the FDA, and is updated regularly.

What is Senna?

Senna has active ingredients of senna. It is often used in constipation. eHealthMe is studying from 37,302 Senna users. Check the latest studies of Senna.

What is Lymphopenia?

Lymphopenia (an abnormally low level of lymphocytes in the blood) is found to be associated with 897 drugs and 1,072 conditions by eHealthMe. Check the latest studies of Lymphopenia.

On Jul, 11, 2026

37,042 people reported to have side effects when taking Senna.
Among them, 29 people (0.08%) have Lymphopenia.

Among these 29 people:

How long have people been on Senna when they have Lymphopenia? *

What is the gender of people who have Lymphopenia when taking Senna? *

female: 48.15 %
male: 51.85 %

What is the age of people who have Lymphopenia when taking Senna? *

What are other drugs people take besides Senna? *

What are other side effects people have besides Lymphopenia? *

Hyperglycemia (high blood sugar): 8 people, 27.59%
Hypocalcaemia (levels of calcium in blood serum are abnormally low): 6 people, 20.69%
Oedema Peripheral (superficial swelling): 6 people, 20.69%
Infection: 6 people, 20.69%
Hypotension (abnormally low blood pressure): 6 people, 20.69%
Hypoalbuminaemia (levels of albumin in blood serum are abnormally low): 5 people, 17.24%
Cough: 5 people, 17.24%
Dyspnea (difficult or laboured breathing): 5 people, 17.24%
Hyperhidrosis (abnormally increased sweating): 4 people, 13.79%
Haematoma (collection of blood outside the blood vessels): 4 people, 13.79%

What are the existing conditions these people have? *

High Blood Pressure: 4 people, 13.79%
Squamous Cell Carcinoma (a cancer of a kind of epithelial cell): 4 people, 13.79%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 13.79%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 13.79%
Tumor Lysis Syndrome: 4 people, 13.79%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 4 people, 13.79%
Pain: 3 people, 10.34%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 3 people, 10.34%
Nausea (feeling of having an urge to vomit): 3 people, 10.34%
Anaemia (lack of blood): 2 people, 6.90%

* Approximation only. Some reports may have incomplete information.

Do you take Senna and have Lymphopenia?

- Check whether Lymphopenia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Senna:

Senna (37,302 reports)

Lymphopenia treatments and more:

Lymphopenia (16,935 reports)

Browse all side effects of Senna:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Lymphopenia:

Lymphopenia (897 drugs)

Browse all the conditions that are associated with Lymphopenia:

Lymphopenia (1,072 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on senna (the active ingredients of Senna) and Senna (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.