Senna and Mean cell volume increased - a phase IV clinical study of FDA data

Summary:

Mean cell volume increased is reported as a side effect among people who take Senna (senna), especially for people who are female, 60+ old, also take Zejula, and have Ovarian cancer.

The phase IV clinical study analyzes which people have Mean cell volume increased when taking Senna. It is created by eHealthMe based on reports of 37,042 people who have side effects when taking Senna from the FDA, and is updated regularly.

What is Senna?

Senna has active ingredients of senna. It is often used in constipation. eHealthMe is studying from 37,302 Senna users. Check the latest studies of Senna.

What is Mean cell volume increased?

Mean cell volume increased (more than normal average red blood cell volume) is found to be associated with 453 drugs and 495 conditions by eHealthMe. Check the latest studies of Mean cell volume increased.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

37,042 people reported to have side effects when taking Senna.
Among them, 11 people (0.03%) have Mean cell volume increased.

Could Senna cause Mean cell volume increased?

Among these 11 people:

What is the gender of people who have Mean cell volume increased when taking Senna? *

female: 66.67 %
male: 33.33 %

What is the age of people who have Mean cell volume increased when taking Senna? *

What are other drugs people take besides Senna? *

What are other side effects people have besides Mean cell volume increased? *

Weakness: 8 people, 72.73%
Red Blood Cell Count Decreased: 8 people, 72.73%
Haemoglobin Decreased: 8 people, 72.73%
Haematocrit Decreased: 7 people, 63.64%
Mean Cell Haemoglobin Increased (more than normal haemoglobin per red blood cell in a sample of blood): 7 people, 63.64%
Fatigue (feeling of tiredness): 7 people, 63.64%
Nausea (feeling of having an urge to vomit): 6 people, 54.55%
Nausea And Vomiting: 5 people, 45.45%
Dizziness: 5 people, 45.45%
Eosinophil Count Increased: 5 people, 45.45%

What are the existing conditions these people have? *

Ovarian Cancer (cancer of ovary): 6 people, 54.55%
Pain In Extremity: 4 people, 36.36%
Nausea (feeling of having an urge to vomit): 4 people, 36.36%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 2 people, 18.18%
Back Pain: 2 people, 18.18%
Neck Pain: 2 people, 18.18%
Malignant Peritoneal Neoplasm (cancer tumour of peritoneum): 2 people, 18.18%
Seborrhoeic Dermatitis (a common, inflammatory skin condition that causes flaky, white to yellowish scales to form on oily areas such as the scalp): 1 person, 9.09%
Iron Deficiency: 1 person, 9.09%
Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Senna and have Mean cell volume increased?

- Check whether Mean cell volume increased is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Senna:

Senna (37,302 reports)

Browse all side effects of Senna:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Mean cell volume increased:

Mean cell volume increased (453 drugs)

Browse all the conditions that are associated with Mean cell volume increased:

Mean cell volume increased (495 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on senna (the active ingredients of Senna) and Senna (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.